UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 14A
PROXY STATEMENT PURSUANT TO SECTION 14(a)
OF THE SECURITIES EXCHANGE ACT OF 1934
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Halozyme Therapeutics, Inc.
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March 20, 202025, 2022
Dear Stockholder:
You are cordially invited to attend the 20202022 Annual Meeting of Stockholders of Halozyme Therapeutics, Inc., which will be held on April 30, 2020,May 5, 2022, at 8:00 a.m. local time, at Halozyme’s main office building located at 11388 Sorrento Valley Road, San Diego, California 92121.Pacific Time. The meeting will be online only, so there is no physical meeting location.
The Notice of Annual Meeting of Stockholders and a Proxy Statement, which describes the formal business to be conducted at the meeting, follow this letter.
It is important that you use this opportunity to take part in the affairs of Halozyme Therapeutics, Inc. by voting on the business to come before this meeting. Whether or not you plan to attend the Annual Meeting in person,online, we hope you vote as soon as possible to assure your representation. You can vote your shares over the Internet, by telephone or by using a traditional proxy card. Instructions on each of these voting methods are outlined in the enclosed proxy statement. Regardless of the number of shares you own, your careful consideration of, and vote on, the matters before our stockholders is important.
A copy of Halozyme’s Annual Report on Form 10-K accompanies these proxy materials for your information. At the Annual Meeting, we will review Halozyme’s activities over the past year and our plans for the future. The Board of Directors and management look forward to seeing you at the Annual Meeting.
Sincerely yours,
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HELEN I. TORLEY, M.B. Ch.B., M.R.C.P.
President and Chief Executive Officer



TABLE OF CONTENTS





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HALOZYME THERAPEUTICS, INC.
11388 Sorrento Valley Road
San Diego, California 92121
NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
To Be Held on April 30, 2020May 5, 2022
TO THE STOCKHOLDERS OF HALOZYME THERAPEUTICS, INC.:
Notice is hereby given that the Annual Meeting of the Stockholders of Halozyme Therapeutics, Inc., a Delaware corporation, will be held on April 30, 2020,May 5, 2022, at 8:00 a.m. local time, at Halozyme’s main office building located at 11388 Sorrento Valley Road, San Diego, California 92121,Pacific Time. The meeting will be online only, so there is no physical meeting location. The Annual Meeting is being held for the following purposes:
1.To elect three Class III directors to hold office for a three-year term and until their respective successors are elected and qualified;
1.To elect three Class I directors to hold office for a three-year term and until their respective successors are elected and qualified;
2.To approve, by a non-binding advisory vote, the compensation of our Named Executive Officers;
3.To ratify the selection of Ernst & Young LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2020; and
4.To transact such other business as may properly come before the Annual Meeting.
2.To approve, by a non-binding advisory vote, the compensation of our Named Executive Officers;
3.To ratify the selection of Ernst & Young LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2022; and
4.To transact such other business as may properly come before the Annual Meeting.
You will be able to attend the Annual Meeting, submit questions and vote during the live webcast by visiting www.virtualshareholdermeeting.com/HALO2022 and entering the 16 digit control number included in your Notice of Internet Availability, on your proxy card, or voting instruction form, or in the instructions you received by email. Please refer to the additional logistical details and recommendations in the accompanying proxy statement. Only stockholders of record at the close of business on March 2, 20207, 2022 are entitled to notice of, and to vote at, this Annual Meeting and any adjournment or postponement thereof. The Board of Directors recommends that you vote FOR each of the proposed nominees to the Board of Directors named in the accompanying Proxy Statement and for the other proposals identified above.
By order of the Board of Directors,
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Masaru MatsudaMark Snyder
Senior Vice President, General Counsel,
and Corporate Secretary
San Diego, California
March 20, 202025, 2022
Important Notice Regarding the Availability of Proxy Materials for
The Annual Meeting of Stockholder Meeting To Be Held on April 30, 2020May 5, 2022
The Proxy Statement and the 20192021 Annual Report to Stockholders and the means to vote by Internet are available at www.proxyvote.com.
IMPORTANT: You are cordially invited to attend the virtual meeting in person.online. Whether or not you expect to attend the virtual meeting online, please vote as soon as possible by using the Internet or telephone or for those receiving paper copies of these proxy materials by completing, signing, dating and mailing your proxy card in the accompanying postage-paid envelope. Even if you have voted by proxy, you may still vote in person if you attend the meeting. Please note, however, that if the record holder of your shares is a broker, bank or other nominee, and you wish to vote at thevirtual meeting you must obtain a proxy issued in your name from that record holder.online.



PROXY STATEMENT FOR ANNUAL MEETING OF STOCKHOLDERS
The accompanying proxy is solicited on behalf of the Board of Directors of Halozyme Therapeutics, Inc., a Delaware corporation (“Halozyme” or the “Company”), for use at Halozyme’s Annual Meeting of Stockholders to be held online on April 30, 2020May 5, 2022 at 8:00 a.m. local time, at Halozyme’s main office building located at 11388 Sorrento Valley Road, San Diego, California 92121,Pacific Time and at any adjournment or postponement thereof, for the purposes set forth in the accompanying Notice of Annual Meeting of Stockholders. This Proxy Statement and the enclosed proxy are being mailed to stockholders on or about March 20, 202025, 2022.
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ANNUAL MEETING AGENDA AND BOARD OF DIRECTOR VOTE RECOMMENDATIONS
Stockholders are being asked to vote on each of the following items at the Annual Meeting:
The election of three Class IIII director nominees named in this Proxy Statement to the Board of Directors, each to serve a three-year term and until their respective successors are elected and qualified;
The approval of a non-binding advisory resolution approving the compensation of our Named Executive Officers; and
The ratification of the selection of Ernst & Young LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2020.2022.
The Board of Directors recommends that you vote FOR the proposed nominees to the Board of Directors named in this Proxy Statement and FOR each of the other proposals described above.
SOLICITATION AND VOTING
Voting Securities.Only stockholders of record as of the close of business on March 2, 2020,7, 2022, the record date for the Annual Meeting, will be entitled to vote at the meeting and any adjournment or postponement thereof. As of that date, we had 138,069,410137,772,750 shares of common stock outstanding, all of which are entitled to vote with respect to all matters to be acted upon at the Annual Meeting. Each stockholder of record as of that date is entitled to one vote for each share of common stock held by him or her. Our Bylaws provide that a majority of all of the shares of the stock entitled to vote, whether present in person or represented by proxy, shall constitute a quorum for the transaction of business at the meeting. When a quorum is present at the meeting, all matters, including the election of directors, will be determined by a plurality of the votes cast by the stockholders entitled to vote at the election (please see the discussion on page 3 of the “majority voting” provisions in our Bylaws), and any other matter will be determined by a majority in voting power of the shares present in person or represented by proxy and entitled to vote on the matter. Votes for and against, abstentions and “broker non-votes” will each be counted as present for purposes of determining the presence of a quorum.
As permitted by rules adopted by the Securities and Exchange Commission, we are furnishing our proxy statement, 20192021 Annual Report to Stockholders and proxy card over the internet to most of our stockholders. This means that most of our stockholders will initially receive only a notice containing instructions on how to access the proxy materials over the Internet. If you would like to receive a paper copy of the proxy materials, the notice contains instructions on how you can request copies of these documents at no cost to you.
Voting of Proxies.All valid proxies received before the meeting will be exercised. All shares represented by a proxy will be voted, and where a proxy specifies a stockholder’s choice with respect to any matter to be acted upon, the shares will be voted in accordance with that specification. If no choice is indicated on the proxy provided by a stockholder of record, the shares will be voted for the nominees and in favor of each other proposal.
You may vote in person by attending the Annual Meeting online, by using the Internet or telephone to submit a proxy or by completing and returning a proxy by mail. You must bring valid, government-issued photo identification to gain admission to the Annual Meeting.
Voting by Internet. To vote by Internet, go to www.proxyvote.com. Internet voting is available 24 hours a day, although your vote by Internet must be received by 11:59 p.m. Eastern Time on April 29, 2020.May 4, 2022. You will need the control number found either on the Notice of Internet Availability of Proxy Materials or on the proxy card if you are receiving a printed copy of these materials. If you vote by Internet, do not return your proxy card or voting instruction card. If you hold your shares in “street name” as


explained below, please refer to the Notice of Internet Availability of Proxy Materials or voting instruction cardform or notice provided to you by your broker, bank or other holder of record for Internet voting instructions.
Voting by Telephone. To vote by telephone, call 1-800-690-6903 and follow the instructions. Telephone voting is available 24 hours a day, although your vote by telephone must be received by 11:59 p.m. Eastern Time on April 29, 2020.May 4, 2022. You will need the control number found either on the Notice of Internet Availability of Proxy Materialsyour voting instruction form, notice or on the proxy card if you are receiving a printed copy of these materials. If you vote by telephone, do not return your proxy card or voting instruction card. If you hold your shares in “street name” as explained below, please refer to the Notice of Internet Availability of Proxy Materials or voting instruction card provided to you by your broker, bank or other holder of record for telephone voting instructions.
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Voting by Mail. By completing, signing and returning the proxy card in the prepaid and addressed envelope enclosed with proxy materials delivered by mail, you are authorizing the individuals named on the proxy card to vote your shares at the Annual Meeting in the manner you indicate. You are encouraged to sign and return the proxy card even if you plan to attend the Annual Meeting so that your shares will be voted if you are unable to attend the Annual Meeting. If you receive more than one proxy card, it is an indication that your shares are held in multiple accounts. Please complete, sign and return all proxy cards to ensure that all your shares are voted.
Voting in Person. You may also vote in person at theOnline During Annual Meeting. A stockholder of record may still attend the meeting and voteYou are entitled to participate in person even if he or she has already voted by proxy. To vote in person, you, as a stockholder of record, may attend the Annual Meeting if you were a shareholder as of the close of business on March 7, 2022, the record date, or hold a legal proxy for the meeting provided by your bank, broker, or nominee. To be admitted to the Annual Meeting at www.virtualshareholdermeeting.com/HALO2022, you must enter the control number found on your proxy card, voting instruction form or notice you previously received. You may vote during the Annual Meeting by following the instructions available on the meeting website during the meeting. The meeting’s virtual attendance format will provide you the ability to participate and obtain a ballot upon arrival.ask questions in writing during the meeting. Whether or not you plan to participate in the Annual Meeting, we urge you to vote and submit your proxy in advance of the meeting by one of the methods described in the proxy materials for the Annual Meeting. If your shares are registered directly in your name with our transfer agent, Corporate Stock Transfer,EQ by Equiniti, you are considered the stockholder of record and you have the right to vote in person at the Annual Meeting. If your shares are held in the name of your broker or other nominee, you are considered the beneficial owner of shares held in “street name.” Beneficial owners whose stock is held in the name of a bank, broker or other nominee generally will receive instructions for voting from their banks, brokers or other nominees, rather than directly from us. You can vote your shares held through a bank, broker or other nominee by following the voting instructions sent to you by that institution. As aShares for which you are the beneficial owner if you wish to vote atbut not the stockholder of record may also be voted electronically during the Annual Meeting, you will need to bring to the Annual Meeting a legal proxy from your broker or other nominee authorizing you to vote those shares.Meeting.
Revocability of Proxies. A stockholder giving a proxy has the power to revoke it at any time before it is exercised by delivering to the Secretary of Halozyme a written instrument revoking the proxy or a duly executed proxy with a later date, or by attending the meetingAnnual Meeting online and voting in person.
Broker Non-Votes. A broker non-vote occurs when a broker submits a proxy card with respect to shares held in street name on behalf of a beneficial owner but is prohibited from voting on a particular matter because the broker has not received voting instructions from the beneficial owner and therefore does not have discretion to vote the beneficial owner’s shares with respect to that matter. Under the rules that govern brokers who are voting with respect to shares held in street name, brokers have the discretion to vote such shares on routine matters, but not on non-routine matters. Routine matters include the ratification of our independent registered public accounting firm. Non-routine matters include the election of directors and the advisory vote on executive compensation.
Solicitation of Proxies. We will bear the entire cost of soliciting proxies for the upcoming meeting. In addition to soliciting stockholders by mail through our employees, we will request banks, brokers and other custodians, nominees and fiduciaries to solicit customers for whom they hold our stock and will reimburse them for their reasonable, out-of-pocket costs. We may use the services of our officers, directors and others to solicit proxies, personally or by telephone, without additional compensation.

We intend to hold our annual meeting in person. However, we are actively monitoring the coronavirus (COVID-19) developments. We are sensitive to the public health and travel concerns our shareholders may have and the protocols that federal, state, and local governments may impose. In the event it is not possible or advisable to hold our annual meeting in person, we will announce alternative arrangements for the meeting as promptly as practicable, which may include holding the meeting solely by means of remote communication. Please monitor our annual meeting website at Halozyme.com for updated information. If you are planning to attend our meeting, please check the website one week prior to the meeting date. As always, we encourage you to vote your shares prior to the annual meeting.
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PROPOSAL NO. 1
ELECTION OF DIRECTORS
We have a classified Board of Directors that currently consists of three Class I directors, two Class II directors and three Class III directors. Our directors are elected for a term of three years, with one class of directors up for election every year. At the 20202022 Annual Meeting of Stockholders, we will be electing three Class III directors, while the Class I directors whilewill be elected at the 2023 Annual Meeting of Stockholders and the Class II directors will be elected at the 2021 Annual Meeting of Stockholders and the Class III directors will be elected at the 20222024 Annual Meeting of Stockholders.
The Class IIII nominees recommended by the Board of Directors for election at the 20202022 Annual Meeting are: Bernadette Connaughton, Kenneth J. KelleyJeffrey W. Henderson, Connie L. Matsui and Matthew L. Posard.Helen I. Torley. Mr. Henderson, Ms. Connaughton, Mr. KelleyMatsui and Mr. PosardDr. Torley are current members of our Board of Directors and, if elected, they will serve as directors until our Annual Meeting in 20232025 or until their successors are elected and qualified. If any nominee declines to serve or becomes unavailable for any reason, or if a vacancy occurs before the election (although we know of no reason to anticipate that this will occur), the proxies may be voted for such substitute nominees as we may designate.
Majority Voting Standard
Our Bylaws provide that in uncontested elections,any election of one or more directors at a meeting at which a quorum is present, other than in a contested election, each director shall be elected by the vote of a majority of the votes cast by the stockholders with respect to the director. If a director does not receive in an election, other than a contested election, a majority of the votes, the director must tender his or her resignation to the Board of Directors if such director receives more “withhold” votes than votes “for” electing the director.Directors. Within 90 days after the date of the certification of the election results, the Nominating and Corporate Governance Committee of the Board of Directors (or other committee that may be designated by the Board of Directors) will make a recommendation to the Board of Directors on whether to accept or reject the resignation, or whether other action should be taken. The Board of Directors will promptly act on such committee’s recommendation and publicly disclose within four business days on a Current Report on Form 8-K filed with the Securities and Exchange Commission (“SEC”) its decision and the rationale behind such decision.
Vote Required
If a quorum is present at the meeting, election of each of the three nominees for Class IIII directors receivingrequires the highest numberaffirmative vote of votes will be elected asa majority in voting power of the Class I directors.shares present in person or represented by proxy at the meeting and voting on the matter. Abstentions and broker non-votes will have no effect on the outcome of the vote.
Recommendation
The Board of Directors recommends a vote “FOR” each of the nominees named above.








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Board Candidate Expertise Selection Criteria
The following table sets forth biographical information for the three Class I nominees to be elected at this meeting as well as all other directors who will continue serving onNominating and Corporate Governance Committee, with input from the Board of Directors, has determined that the following this meeting:areas of expertise are of particular importance in providing appropriate oversight of the Company’s business and operations. Accordingly, the Nominating and Corporate Governance Committee seeks candidates for the board of directors from diverse professional backgrounds in order to ensure that the board of directors is comprised of individuals possessing extensive expertise in one or more of the following areas:
SkillRationale
Medicine and ScienceAs a Company directly and indirectly involved in the development, approval and commercialization of drugs, expertise in medicine and science is a key to the ongoing assessment of potential new technologies we may acquire.
Pharma Business Leadership and Operations
Experience in, and knowledge of, the pharmaceutical business contributes to deep understanding of business strategy, operations, key performance indicators and the competitive environment.
Complimentary Business/Industry Segment ExperienceDiverse experience gained from adjacent and complimentary industries contributes to identification and evaluation of new opportunities and ideas.
International BusinessInternational Business experience adds to our understanding of diverse business environments, economic conditions and cultural perspectives that informs our global business initiatives and strategy.
Human Capital Management

Execution of our strategy requires the development and retention of highly skilled and diverse set of leaders and team members.
Finance and Capital MarketsExperience overseeing financial transactions provides knowledge and skills necessary to evaluate and oversee the Company’s design and implementation of financial and capital allocation strategies.
M&AExperience in the identification, negotiation and execution of M&A transactions provides knowledge to oversee the Company’s potential M&A activities.
Risk ManagementExperience in risk management contributes to the identification, prioritization, assessment and mitigation of significant risk facing the company.











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Name  Age 
Director
Since
 Position with the Company
Class I directors nominated at the 2020 Annual Meeting of Stockholders:
Bernadette Connaughton 61 2018 Director
Kenneth J. Kelley 60 2004 Director
Matthew L. Posard 52 2013 Director
Class II directors whose terms expire at the 2021 Annual Meeting of Stockholders:
Jean-Pierre Bizzari, M.D. 65 2015 Director
James M. Daly 58 2016 Director
Class III directors whose terms expire at the 2022 Annual Meeting of Stockholders:
Jeffrey W. Henderson 55 2015 Director
Connie L. Matsui 66 2006 Chair of the Board of Directors
Helen I. Torley, M.B. Ch.B., M.R.C.P. 57 2014 President, Chief Executive Officer & Director


Based on its review of each director’s professional experience and background, the Nominating and Corporate Governance Committee has determined that our current board members possess expertise in the following areas noted below:

DirectorMedicine and SciencePharma Business Leadership and OperationsComplimentary Business/Industry Segment ExperienceInternational BusinessHuman Capital ManagementFinance and Capital MarketsM&ARisk Management
Jean-Pierre Bizzari, M.D.XXX
Bernadette ConnaughtonXXX
James M. DalyXX
Jeffrey W. HendersonXXXXXXX
Connie L. MatsuiXXXX
Matthew L. PosardXXXXX
Moni MiyashitaXXXX
Helen I. Torley, M.B. Ch.B., M.R.C.P.XXXXX
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Board Diversity
Based upon responses received from each of our directors with respect to diversity, the Company’s Board of Directors is currently comprised of individuals from the following diverse backgrounds:

Board Diversity Matrix (As of March 25, 2022)
Total Number of Directors8
FemaleMaleNon-BinaryDid Not Disclose Gender
Part I: Gender Identity
Directors4400
Part II: Demographic Background
African American or Black0000
Alaskan Native or Native American0000
Asian2000
Hispanic or Latinx0000
Native Hawaiian or Pacific Islander0000
White2400
Two or More Races or Ethnicities0000
LGBTQ+0
Did Not Disclose Demographic Background0

Directors Nominated for Election at the 20202022 Annual Meeting

Jeffrey W. Henderson (age 57)
Director Since: 2015

Board Committees: Audit Committee (Chair), Compensation Committee

Key Skills: Pharma Business Leadership and Operations, Complimentary Business/Industry Segment Experience, International Business, Human Capital Management, Finance and Capital Markets, M&A, Risk Management

Other Current Public Boards:
Becton Dickinson and Company, a medical technology company
Fibrogen, Inc., a biotechnology company
Qualcomm, Inc., a wireless communications and semiconductor company

Mr. Henderson brings nearly 30 years of financial, commercial and pharmaceutical industry expertise to the Board of Directors. He has served as President of JWH Consulting LLC, an investment and business advisory firm, since January 2018. From 2015 to 2019, he served as a Healthcare Advisory Director to Berkshire Partners LLC. Mr. Henderson previously served as the Chief Financial Officer of Cardinal Health, Inc., a multinational health care services company, from May 2005 to November 2014, and in an executive capacity until his retirement from Cardinal in August 2015. From 1998 to 2005, Mr. Henderson held various senior management positions at Eli Lilly and Company, a multinational pharmaceutical company, including President and General Manager, Eli Lilly Canada, Inc. and Controller and Treasurer of Eli Lilly, Inc. He received his BS in electrical engineering from Kettering University, Flint, Mich., and his MBA from Harvard Graduate School of Business Administration.

Key Skills and Experience:

Pharma Business Leadership and Operations and International Business
Mr. Henderson gained deep experience in a broad range of business and operational topics during his nearly 10-year tenure as Chief Financial Officer for Cardinal Health, a $100 billion health care products and services company. During a portion of this tenure he was also responsible for commercial operations in China and Canada. These experiences built on prior expertise, specifically gained in pharmaceuticals, when he served as general manager of Eli Lilly Canada and Controller/Treasurer of Eli Lilly Inc.
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Complimentary Business/Industry Segment Experience
As a member of the board of directors of Becton Dickinson, a leading global medical technology company, and during his time as an executive at Cardinal Health, Mr. Henderson has gained a deep exposure to, and experience in, key aspects of the medical device business and market.

Finance and Capital Markets and M&A
In his almost 15 years experience as Chief Financial Officer at Cardinal Health and Controller/Treasurer at Eli Lilly, Mr. Henderson gained extensive experience in finance and capital markets. During his tenure at Cardinal Health, the company acquired more than 30 companies, spun-off or sold multi-billion-dollar businesses and expanded into new geographic locations and market segments. During his time with the PE firm of Berkshire Partners, he was involved in the identification, evaluation and execution of multiple acquisition opportunities in the healthcare sector.

Risk Management
In his positions as a Chief Financial Officer for Cardinal Health and Controller/Treasurer at Eli Lilly, Mr. Henderson played a key role in risk identification and risk mitigation. Further, Mr. Henderson has been operationally accountable for commercial operations in both China (Cardinal Health) and Canada (Eli Lilly and Cardinal Health). These unique experiences in both staff and line roles enable a broad perspective on identifying potential risks and risk management.

Human Capital Management
Mr. Henderson has substantial experience leading organizations with multi-thousands of employees, including related aspects of organizational and compensation/incentive design.

Board Service Selection Criteria: As further described in Mr. Henderson’s biography, the Nominating and Corporate Governance Committee believes Mr. Henderson has the relevant background in the following areas which the committee believes are important to service on the Company’s Board of Directors: (i) pharma business leadership and operations, (ii) complimentary business and industry segment experience, (iii) international business, (iv) human capital management, (v) finance and capital markets, (vi) M&A and (vii) risk management. Mr. Henderson’s extensive experience serving in executive leadership positions, including as Chief Financial Officer with large publicly-traded healthcare and pharmaceutical corporations, combined with his business acumen and judgment, including his qualifications as an audit committee financial expert, provide our Board with valuable financial, strategic and operational expertise and leadership skills, leading the Nominating and Corporate Governance Committee to determine that Mr. Henderson should serve as one of our directors.

Connie L. Matsui (age 68)
Director Since: 2006

Chair of the Board

Key Skills: Pharma Business Leadership and Operations, International Business, Human Capital Management, Risk Management, M&A

Other Current Public Boards:
Artelo Biosciences, Inc. a biopharmaceutical company
Sutro Biopharma, Inc., a biopharmaceutical company

Ms. Matsui brings 30 years of pharmaceutical and biotech industry expertise to the Board of Directors. She retired from Biogen Idec Inc., a biotechnology company, in January 2009 as the Executive Vice President, Knowledge and Innovation Networks. She served as an Executive Committee member at both Biogen Idec and IDEC Pharmaceuticals, a predecessor of Biogen Idec. Among the many major roles she played after joining IDEC Pharmaceuticals in November 1992 was Senior Vice President, overseeing investor relations, corporate communications, human resources, project management and strategic planning. Prior to entering the biotechnology industry, Ms. Matsui worked for Wells Fargo Bank in general management, marketing and human resources. She received her BA and MBA from Stanford University.

Key Skills and Experience:

Pharma Business Leadership and Operations
Ms. Matsui gained deep experience in a broad range of business and operational topics during her tenure at IDEC Pharmaceuticals and then Biogen Idec, overseeing human resources, alliance management, investor relations, corporate communications, project management and strategic planning. In addition, she served as Collaboration Chair for the late stage development and commercialization of rituximab (tradenames: Rituxan®, MabThera®) in partnership with Roche and Genentech, a position requiring strong alliance management and business expertise. She also served as project team leader for
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the late stage development and commercialization of Zevalin, the first FDA-approved radioimmunoconguate for the treatment of cancer.

International Business
In her Collaboration Chair position for rituximab, Ms. Matsui served as the IDEC member of the collaboration oversight team with counterparts from Roche, Genentech and Zenyaku Kogyo, responsible for progress on all aspects of late stage development, manufacturing, regulatory approval and global commercialization. In addition, as IDEC’s Project Leader for Zevalin, she worked with leadership at global partner Schering AG based in Germany and radioisotope supplier Nordion, which had nuclear facilities in Canada and Belgium. At Biogen Idec, she was directly responsible for staff teams based in the U.S. and Europe.

Human Capital Management
Ms. Matsui also led Human Resources at IDEC Pharmaceuticals and Biogen Idec, where key experiences included the growth of IDEC from a 100-employee R&D entity to a 1,000-employee fully integrated biotech company and, ultimately, to 4,000 employees worldwide following the merger of equals between IDEC and Biogen. Prior to this position, Ms. Matsui also held various operating positions, including a senior Human Resources position in the banking industry, where experiences were gained in the area of human capital management and integration of merged and acquired entities.

M&A
As Co-Integration lead for the Biogen IDEC merger of equals, Ms. Matsui was engaged in assessing merger feasibility and strategic acceleration potential and had a leading role in communication and implementation of merger plans. This experience included the divestiture of IDEC’s large scale manufacturing plant and successful integration by Genentech and, later on, assimilation of a small-molecule company in San Diego. Ms. Matsui has also guided multiple nonprofit mergers to optimization and facilitated the rapid assimilation of acquired banks and savings & loans while at Wells Fargo.

Risk Management
In her more than 30 years in the biotech industry, initially as an executive officer and then while serving on the board of directors for biotechnology and pharmaceutical companies, Ms. Matsui has provided guidance to companies in a highly regulated industry in managing and mitigating risks in the following areas: corporate restructuring, financing transactions, data communication, employee retention and ESG.

Board Service Selection Criteria: As further described in Ms. Matsui’s biography, the Nominating and Corporate Governance Committee believes Ms. Matsui has the relevant background in the following areas which the committee believes are important to service on the Company’s Board of Directors: (i) pharma business leadership and operations, (ii) international business, (iii) human capital management, (iv) risk management and (v) M&A. Ms. Matsui's operational experience, including her extensive knowledge of the biotechnology industry, her service in other public company management teams and her prior business experience, combined with her business acumen and judgment, provide our Board with valuable management and operational expertise and leadership skills, leading the Nominating and Corporate Governance Committee to determine that Ms. Matsui should serve as one of our directors.

Helen I. Torley, M.B. Ch.B., M.R.C.P. (age 59)
Director Since: 2014

President and Chief Executive Officer

Key Skills: Medicine and Science, Pharma Business Leadership and Operations, Human Capital Management, Finance and Capital Markets, Risk Management

Other Current Public Boards:
Quest Diagnostics Incorporated, a diagnostic information services company

Dr Torley brings over 30 years of drug development, drug commercialization and general management expertise in pharmaceutical and biotechnology to the Board of Directors. She has served as CEO of Halozyme since 2014, successfully leading the company through a critical strategic transition in 2019. Dr Torley previously served as Chief Commercial Officer at Onyx Pharmaceuticals from 2011-2013, leading the successful US launch for Kyprolis ® (Carfilzomib), until the acquisition of Onyx by Amgen in 2013. From 2002-2011 Dr Torley held several senior commercial positions at Amgen including Vice President and General Manager US Bone Health and Vice President and General Manager US Nephrology. In these positions she led the successful launches of Prolia® (denosumab) and Sensipar® (cinacalcet) and significantly grew Epogen® (Epoetin alfa) and Aranesp® (darbepoetin alfa) revenue. From 1997-2002 she held a range of senior sales and marketing leadership positions at Bristol Myers Squib. She began her industry career at Sandoz, which merged with Ciba-Geigy to become Novartis in 1996, where she held a range of positions of increasing responsibility in Clinical Development, culminating in the position of
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Vice President of Medical Affairs, responsible for overseeing the design and conduct of a broad portfolio of clinical studies across nephrology, rheumatology, oncology and CNS indications. She received her M.B.Ch.B. degree (US equivalent to MD) from the University of Glasgow, Scotland and her M.R.C.P from the Royal College of Physicians, Glasgow, Scotland.

Key Skills and Experience:

Medicine and Science
Dr. Torley is a trained physician who while in clinical practice specialized in Internal Medicine and Rheumatology. She served in leadership positions at Sandoz/Novartis from1990 to 1997, most recently as Vice President, Medical Affairs where she oversaw the design and conduct of Phase 1 through 4 clinical studies across multiple disease areas. While at Sandoz/Novartis she led clinical development programs for new products being evaluated in organ transplantation and rheumatoid arthritis and wrote and submitted New Drug Application filings. She has led and played key strategic positions in multiple successful FDA Advisory Committee meetings including for Neoral® (cyclosporin) in Rheumatoid Arthritis, Neoral (cyclosporin) in Organ Transplantation, Epogen® (Epoetin alfa) in anemia in chronic renal failure and HyQvia (immune Globulin infusion 10% with Recombinant Human Hyaluronidase) in Primary Immune Deficiency.

Pharma Business Leadership and Operations
Dr. Torley gained deep experience in a broad range of business and operational topics in her commercial positions. In particular, as General Manager of Bone Health and Nephrology at Amgen and as Chief Commercial Officer at Onyx, she was responsible for hiring and leading sales and marketing organizations, including hiring and training a more than 650-person team for a new drug launch, working on policy topics related to her products and leading three successful new product launches.

Human Capital Management
Dr. Torley has substantial experience leading large organizations, ranging from 120 to approximately 700 people. Her human capital management experiences include hiring and successfully onboarding large new sales teams into an established culture and effective reorganizations as dictated by changes in strategy. She has a strong focus on and understanding of the important role organizational culture, diverse teams, talent development and accountability play in driving results and success.

Finance and Capital Markets
As CEO of Halozyme, Dr. Torley has gained experience in Finance and Capital Markets including direct experience with raising $1 billion through follow-on offerings and through two convertible debt offerings, and executing two share repurchase programs resulting in over $600 million in capital returned to stockholders to date.

Risk Management
In her position as CEO of Halozyme, Dr. Torley plays a key role in risk identification and mitigation. In addition, in her previous positions with other organizations as Chief Commercial Officer and General Manager in which she was accountable for commercial launches, a key accountability was risk identification and mitigation. This wide range of experiences enable a broad perspective on identifying potential risks and executing appropriate mitigations strategies.

Board Service Selection Criteria: As further described in her biography, the Nominating and Corporate Governance Committee believes Dr. Torley has the relevant background in the following areas which the committee believes are important to service on the Company’s Board of Directors: (i) medicine and science, (ii) pharma business leadership and operations, (iii) human capital management, (iv) finance and capital markets and (v) risk management. Dr. Torley's extensive commercial and operational experience, including successful launches of products, and her deep knowledge of the biotechnology industry and the competitive environment, her service as our Chief Executive Officer, combined with her business acumen and judgment, provide our Board with valuable commercial and operational expertise and leadership skills, leading the Nominating and Corporate Governance Committee to determine that Dr. Torley should serve as one of our directors.

Directors Continuing in Office Until the 2023 Annual Meeting

Bernadette Connaughton. (age 63)
Director Since: 2018

Board Committees: Compensation Committee (Chair)

Key Skills: Pharma Business Leadership and Operations, International Business, Human Capital Management

Other Current Company Public Boards:
Editas Medicine, Inc., a clinical stage biotechnology company
Syneos Health Inc., a biopharmaceutical services company
Zealand Pharma A/S, a biotechnology company
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Ms. Connaughton brings more than 30 years of global strategic, commercial and biopharmaceutical industry expertise to the company. From 2004 to October 2017,Board of Directors. Ms. Connaughton retired from Bristol-Myers Squibb Pharmaceutical Company, a multinational pharmaceutical company, where she served in senior management positions at Bristol-Myers Squibb Pharmaceutical Company,from 2004 to October 2017. She most recently serving as president, China, Latin America, Central and Eastern Europe and Middle East. In this position, she developed the multi-year strategy for the successful commercialization of a number of oncology, virology and immunology products, including Opdivo®, Yervoy®, Sprycel®, Daklinza® and Orencia®. Prior to serving in that role, Ms. Connaughton served as Bristol-Myers Squibb’s president, European Markets, Canada and Australia; president, Intercontinental; president, Japan, Pacific Rim, Australia and Canada; senior vice president, Cardiovascular and Metabolic Business Unit, U.S.; and senior vice president, Primary Care Marketing, U.S.President, Intercontinental Region. Ms. Connaughton was recently a member of the board of directors of Visterra, Inc., a private clinical stage biotechnology company, acquired by Otsuka. She also previously served on the European Federation of Pharmaceutical Industry Association, Patient Access and European Markets Committees from 2014 to 2016. She currently serves on the board of directors of Syneos Health, Inc., a biopharmaceutical services company, and Zealand Pharma A/S, a biotechnology company. SheCommittees. Ms. Connaughton received her B.A.BA from Johns Hopkins University and her M.B.A.MBA from The Wharton School, University of Pennsylvania.

TheKey Skills and Experience:

Pharma Business Leadership and Operations
Ms. Connaughton’s extensive experience in business and operations was developed during her 30-year career at Bristol-Myers Squibb where she built a consistent track record of achieving sales growth, improving profitability and transforming operational models in U.S. and international markets. She built expertise and demonstrated success across a wide range of therapeutic areas, including cardiovascular, metabolic diseases, virology and oncology.

International Business
Through her positions leading large global business regions for Bristol Myers Squibb, Ms. Connaughton brings deep experience in international markets. Specific achievements include developing and leading execution of the multi-year strategy for the successful commercialization of Opdivo®, Yervoy®, Sprycel®, Daklinza® and Orencia®. She most recently served as President Intercontinental Region, which included China, Latin America, Central and Eastern Europe and Middle East. Other positions included President, European Markets, Canada and Australia; President, Intercontinental Region; and President, Japan, Pacific Rim, Australia and Canada.

Human Capital Management
In each of her senior management positions, Ms. Connaughton led diverse, cross-functional teams, building the capabilities to successfully develop and commercialize pharmaceutical products. She has broad experience selecting and developing talent and building high performance teams with the skills, motivation and culture to achieve sustainable results.

Board Service Selection Criteria: As further described in Ms. Connaughton’s biography, the Nominating and Corporate Governance Committee believes thatMs. Connaughton has the relevant background in the following areas which the committee believes are important to service on the Company’s Board of Directors: (i) pharma business leadership and operations, (ii) international business and (iii) human capital management. Ms. Connaughton’s extensive operations and commercialization experience in the pharmaceutical industry including the development of successful commercialization strategies for a number of oncology products and her consistent track record of achieving sales growth provides valuable experience and perspective to our Board, leading the Nominating and Corporate Governance Committee to determine that Ms. Connaughton should serve as one of our directors.
Kenneth J. Kelley. Mr. Kelley brings over 35 years of entrepreneurial, venture capital, operational and technical biotechnology experience to Halozyme. He is currently Chairman of the Board and mentor to the CEOs of four privately held biotechnology companies and an advisor to various publicly held biotechnology companies. From 2016 to 2018, Mr. Kelley served as a White House Presidential Executive Fellow and a Senior Advisor to the U.S. National Institutes of Health and the National Institute of Allergy and Infectious Diseases, Vaccine Research Center and to the Assistant Secretary of Preparedness and Response. From 2015 to 2016, Mr. Kelley served as an Advanced Leadership Fellow at Harvard University working on global preparedness for epidemics and pandemics. From 2007 to 2015, Mr. Kelley served as the Chief Executive Officer of privately-held PaxVax, Inc., a specialty vaccine company acquired by Emergent BioSolutions, Inc. Previously, Mr. Kelley was a General Partner at Latterell Venture Partners, where he made investments in early stage biotechnology and medical device startups. Mr. Kelley founded IntraBiotics Pharmaceuticals in 1994 and for over eight years served as CEO, Director and Chair of the Board of Directors. Earlier, Mr. Kelley was an Associate at Institutional Venture Partners (IVP), where he participated in the financing of biotech and medical companies. Prior to IVP, he was a consultant for McKinsey & Company and a scientist at Integrated Genetics (acquired by Genzyme). Mr. Kelley earned an M.B.A. from Stanford University and a B.A. in Biochemical Sciences from Harvard University and is a Fellow in the American Institute for Medical and Biological Engineering.
TheMatthew L. Posard (age 54)
Director Since: 2013

Board Committees: Nominating and Corporate Governance Committee believes that (Chair), Audit Committee

Key Skills: Medicine and Science, Complimentary Business/Industry Segment Expertise, International Business, Human Capital Management, M&A

Other Current Public Boards:
DermTech, Inc. (Chairman), a precision dermatology company
Nautilus Biotechnology, Inc., (Chairman) a development stage life sciences company
Talis Biomedical, a developer of diagnostic tests for infectious diseases

Mr. Kelley’s strategicPosard brings over 30 years of general management and operationalcommercialization experience including his extensive experience as a venture capitalist in the biotechnology and diagnostics industry and his prior executive management experience, combined with his business acumen and judgment, provide ourto the Board of Directors with valuable insight, operational expertise and leadership skills, leading the Nominating and Corporate Governance Committee to determine that Mr. Kelley should serve as one of our directors.
Matthew L. Posard. Mr. Posard provides our Board of Directors with extensive sales, marketing and general management experience in the life sciences and diagnostics industry. Mr. PosardDirectors. He is Founding Principal of Explore DNA, a life sciences executive consulting firm.firm, a position he has held since March 2016. Since 2017, Mr. Posardhe has provided advisory services to CEOs for several emerging life sciences companies. From February 2017 to April 2018, Mr. Posard served as President and Chief Commercial Officer of GenePeeks, Inc., a computational genomics company focused on transforming genetic disease risk analysis.research company. From March 2015 to April 2016, Mr. Posardhe served as Chief Commercial Officer of Trovagene, Inc., a molecular diagnostic biotechnology company wherecompany. From February 2006 to February 2015, he oversaw sales, marketing, client services and market and business development. Prior to joining Trovagene, Mr. Posard held multiplevarious commercial and general management leadership roles since 2006 on the executive team ofpositions at Illumina, Inc., a genomics company focusing on DNA sequencing, and array based technologies, including Vice President ofsenior executive positions overseeing Global Sales, Marketing, and later Vice PresidentGeneral Manager of Global Sales whereClinical and Consumer Genomics as well as New and Emerging Markets. Mr. Posard holds a BA degree in Management Science from the University of San Diego.
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Key Skills and Experience:

Medicine and Science
Mr. Posard has deep expertise introducing novel and transformative products to medical and research markets while scaling organizations efficiently. He is a Founding Principal of Explore DNA and provides advisory services to executive officers of several emerging life sciences companies.

Complementary Business/Industry Segment Expertise
Mr. Posard adds to his biotech expertise with deep knowledge in the diagnostics area, having served in senior positions at Illumina, Biosite, Inc. and Gen-Probe, Inc. At Illumina he was part of the executive management team that led Illuminathe company to its first $1 billion in revenue. Mr. Posard also served as Senior Vice President and General Manager of Illumina’s new and emerging market opportunities business as well as the General Manager of its translational and


consumer genomics business. Previously, Mr. Posard held commercial leadership roles in sales and marketing atAt Biosite Inc., where he was instrumental in the successful introduction of the company’s BNP congestive heart failure biomarker and its BNP co-marketing collaboration with Beckman Coulter. Additionally,At Gen-Probe, Mr. Posard held various positions in strategic and product marketing at Gen-Probe, Inc., helpinghelped the company attain leading market positions in DNA probe-based infectious disease diagnostics and blood banking.

International Business
Mr. Posard serveshas extensive international business experience, having served as the Vice President of Global Sales for Illumina where he led an international commercial sales team. He also served as Senior Vice President and General Manager of Illumina’s Translational and Consumer Genomics and New and Emerging Markets business units and was responsible for over $100 million of sales growth in his first year in this position. This experience provided substantial exposure to commercial markets around the world.

Human Capital Management
In his senior commercial marketing positions with various companies, Mr. Posard has managed and led a number of large and diverse marketing teams. A seasoned executive in the genomics and life science space, Mr. Posard has extensive background in effectively scaling organizations.

M&A
Mr. Posard has served on the board of directors and in senior leadership positions at a variety of DermTech, Inc., a precision dermatology company. He holds a B.A. degree in Management Science from the University of California, San Diegostartup and emerging companies and has been NACD board certified through UCLA’s Anderson Schoolextensive experience in the area of Business boardmergers and acquisitions in the biotech and diagnostics space. In his position as advisor to senior executives of director certification program.life science companies, he has provided guidance and effective consultation in the execution of strategic acquisitions.
The
Board Service Selection Criteria: As further described in his biography, the Nominating and Corporate Governance Committee believes that Mr. Posard’sPosard has the relevant background in the following areas which the committee believes are important to service on the Company’s Board of Directors: (i) medicine and science, (ii) complimentary business and industry segment expertise, (iii) international business, (iv) human capital management and (v) M&A. Mr. Posard's general management, sales and marketing experience including the successful launch of products and management of sales operations provides valuable experience and perspective to our Board, of Directors, leading the Nominating and Corporate Governance Committee to determine that Mr. Posard should serve as one of our directors.

Moni Miyashita (age 66)
Director Since: 2022

Key Skills: Complimentary Business/Industry Segment Expertise, International Business, M&A, Risk Management

Ms. Miyashita brings over 25 years of global experience leading business transformations and building new businesses through strategy, new business models, and mergers & acquisitions. Since May 2019, she has served as the Chief Strategy Officer of Valo Health, LLC, a technology company built to transform the drug discovery and development process using human-centric data and artificial intelligence computation. Prior to Valo Health, from August 2015 to May 2019, she was a Partner at Innosight Consulting, where she provided growth strategy consulting services for businesses in the biotech, healthcare and technology industries. From 2011 to 2015, she was a Senior Advisor at McKinsey where she advised senior executive leadership teams on executing strategic M&A. Prior to McKinsey, she served as Vice President, Corporate Development at IBM Corporation, an information technology company, from 1998 to 2011. She received her BS degree in marketing from the University of Colorado and her MBA from the University of Denver.

Key Skills and Experience:

Complementary Business/Industry Segment Expertise
In 2019, Ms. Miyashita joined Valo Health as Chief Strategy Officer where she develops and drives complex business models, building a disruptive technology platform, and applying it to drug discovery, clinical development, and strategic partnerships across a regulated pharmaceutical ecosystem. While serving as Partner at Innosight Consulting, she advised and supported
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CEOs and their executive leadership teams on disruptive growth strategies in the biotech and healthcare industries. While serving as Senior Advisor at McKinsey, Ms. Miyashita provided global advisory services on M&A to executive and senior leadership teams across the pharmaceutical, biotech, and healthcare industries.

International Business and M&A
During her tenure as Vice President at IBM, Ms. Miyashita was a key architect in developing and executing M&A globally, anchored on strategy, with successful deal flow, transaction execution and post-merger integration. This strategy and effort resulted in over 40 quarters of double-digit earnings per share growth and creating the highest revenue and market capitalization in IBM’s history. Prior to this position, Ms. Miyashita had executive positions in IBM Asia. While serving as Senior Advisor at McKinsey, Ms. Miyashita helped build McKinsey’s M&A practice and provided global advisory services to executive and senior leadership teams in the Americas, Europe, and Asia on transforming and growing their businesses through M&A.

Risk Management
During her tenure as Vice President at IBM, Ms. Miyashita was involved in over 100 acquisitions or transactions and multiple business carve outs for divestiture from IBM to other companies which included developing cross functional processes and approaches to manage risk. Under her leadership, cross functional teams prepared for and passed multiple business audits to ensure risk was identified, mitigated and managed for executing all acquisitions.

Board Service Selection Criteria: As further described in Ms. Miyashita’s biography, the Nominating and Corporate Governance Committee believes Ms. Miyashita has the relevant background in the following areas which the committee believes are important to service on the Company’s Board of Directors: (i) complementary business and industry experience, (ii) international business, (iii) M&A and (iv) Risk Management. Ms. Miyashita’s extensive experience in developing and executing complex corporate transactions and her experience providing strategy execution advice to senior leadership teams provide our Board with valuable strategic and operational expertise, leading the Nominating and Corporate Governance Committee to determine that Ms. Miyashita should serve as one of our directors.

Directors Continuing in Office Until the 20212024 Annual Meeting
Jean-Pierre Bizzari M.D. (age 67)
Director Since: 2015

Board Committees: Nominating and Corporate Governance Committee, Compensation Committee

Key Skills: Medicine and Science, Pharma Business Leadership and Operations and International Business

Other Current Public Boards:
Compugen Ltd., a biotechnology company
Nordic Nanovector ASA, a biotechnology company
Transgene S.A.., a biopharmaceutical company

Recent Past Public Company Board Experience: Pieris Pharmaceuticals, Inc., iTeos Therapeutics S.A. and Onxeo S.A (Dr. Bizzari stepped down from the Onxeo board in 2021).

Dr. Bizzari provides our Board of Directors with overbrings more than 30 years of clinical oncologypharmaceutical and global drug approval strategy expertise.biotech industry expertise to the Board of Directors. He retired from Celgene Corporation, a global pharmaceutical company, having served as Executive Vice President and Global Head of Oncology from October 2012 to December 2015 and as Senior Vice President for Clinical Development Oncology from 2008 to October 2012, and2012. While at Celgene, Dr. Bizzari oversaw the development and approval of a number of leading oncology products including REVLIMID® (lenalidomide), VIDAZA® (azacitidine), ISTODAX® (romidepsin) and ABRAXANE® (nab-paclitaxel). Prior to 2008, Dr. Bizzari served as Vice President, Clinical Oncology Development for Sanofi-Aventis where he oversaw the approval of Eloxatin® (oxaliplatin), Taxotere® (docetaxel) and Elitek®(rasburicase). Dr. Bizzari was also Vice President, Clinical Development Oncology for Rhône-Poulenc Rorer. Dr. Bizzari is a member of the Scientific Advisory Board of France’s National Cancer Institute. Dr. Bizzari has also been a member of the international scientific committee of the French National Cancer Research Institute since 2005 and the French National Cancer Institute (INCa) since 2010. Dr. Bizzari also serves on the board of directors of Transgene SA, a biopharmaceutical company, and biotechnology companies Compugen Ltd., Pieris Pharmaceuticals, Inc. and Nordic Nanovector ASA. Within the past five years he also served on the board of directors of Celator Pharmaceuticals, Inc., a biopharmaceutical company, and iTeos Therapeutics S.A, a biotechnology company. He also serves as a board observer at Onxeo S.A.products. Dr. Bizzari is a Doctor of Medicine and a graduate of the Nice Medical School and a specialist in oncology (training in Toronto and Montreal). Dr. Bizzari was also an assistant in the medical oncology department at La Pitié-Salpêtrière hospital in Paris.

TheKey Skills and Experience:

Medicine and Science
Dr. Jean-Pierre Bizzari served in senior positions at Celgene from 2008 to 2015, most recently as Executive Vice President, group head, and clinical oncology development. Prior to this, he spent 15 years as Vice President, Clinical Development Oncology at Rhône-Poulenc Rorer, Aventis and as Vice President, Clinical Oncology Development at Sanofi-Aventis and has been involved in the clinical development of multiple anticancer agents such as Taxotere®, Eloxatin®, Revlimid®, Vidaza®, Abraxane®, Irinotecan® (CPT-11). Dr. Bizzari is a world-renowned oncology expert and is a member of the scientific advisory board of the French National Cancer Institute (INCa) and is chair of the New Drug Advisory Committee at the European Organization of Research and Treatment of Cancer (EORTC).
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Pharma Business Leadership and Operations and International Business
In his position as an oncology leader accountable for the execution of a broad range of large clinical studies, Dr. Bizzari led or provided valuable input into a broad range of topics including oncology development strategy for Celgene and Rhône Poulenc Rorer, regulatory strategy, regulatory environment, safety assessment, global studies and market (including Japan and China), manufacturing needs and strategy, biostatistics and data communication. Dr. Bizzari has extensive experience serving on the boards of directors for several international companies.

Board Service Selection Criteria: As further described in Dr. Bizzari’s biography, the Nominating and Corporate Governance Committee believes that Dr. Bizzari has the relevant background in the following areas which the committee believes are important to service on the Company’s Board of Directors: (i) medicine and science, (ii) pharma business leadership and operations and (iii) international business. Dr. Bizzari’s track record of success in developing strategies that have resulted in global approvals for some of the world’s most important cancer drugs provides our Board of Directors with valuable strategic expertise in both oncology drug development and global commercialization, leading the Nominating and Corporate Governance Committee to determine that Dr. Bizzari should serve as one of our directors.

James M. Daly. (age 60)
Director Since: 2015

Board Committees: Audit Committee, Nominating and Corporate Governance Committee

Key Skills: Pharma Business Leadership and Operations, International Business

Other Current Public Company Boards:
Acadia Pharmaceutical, Inc., a biopharmaceutical company
argenx S.E, a biopharmaceutical company
Bellicum Pharmaceuticals, Inc., a biopharmaceutical company
Madrigal Pharmaceuticals, Inc., a biopharmaceutical company

Recent Past Public Company Board Experience: Chimerix, Inc.

Mr. Daly is an advisorbrings more than 30 years of experience leading U.S. and global pharmaceutical businesses to the Board of Directors. He retired from Incyte Corporation, a number of biotechnology companies. Previously,biopharmaceutical company, where he served as Executive Vice President and Chief Commercial Officer at Incyte Corporation, a biopharmaceutical company, a position he held from October 2012 to June 2015. Prior to joining Incyte, Mr. Daly served in various senior management and commercial positions at Amgen, Inc., a global pharmaceutical company, from January 2002 to December 2011. Prior to Amgen, he worked at GlaxoSmisthKline from 1985 to 2001 in various positions of increasing responsibilities. Mr. Daly earned a BS degree in Pharmacy and his MBA from the University at Buffalo.

Key Skills and Experience:

Pharma Business Leadership and Operations
Over the course of his career, Mr. Daly has built market-leading global franchises across multiple therapeutic categories, with a particular focus in oncology. As Executive Vice President and Chief Commercial Officer at Incyte Corporation, he was instrumental in re-accelerating the launch of Jakafi®, and driving sustained future growth. At Amgen he oversaw multiple successful U.S. product launches, including Aranesp®, Neulasta®, Vectibix®, Nplate®, Xgeva® and Prolia®.

International Business
In his position as Senior Vice President of North America Commercial Operations, Global Marketing and Global Marketing/Commercial Development at Amgen, Inc., a global pharmaceutical company where he was employed from January 2002 to December 2011. Prior to his employment withfor Amgen, Mr. Daly was Senior Vice Presidentled P&L responsibility for all U.S. and General Manager of the Respiratory/Anti-Infective business unitCanadian businesses and had oversight for global commercialization strategy for new product launches. In this position he gained experience in multiple diverse healthcare systems. While at GlaxoSmithKline, where he was employed from June 1985 to December 2001. Within the past five years,GSK, Mr. Daly served onworked in the board of directors of Chimerix, Inc., a biopharmaceutical company.German affiliate in Hamburg, Germany.

Board Service Selection Criteria: As further described in Mr. Daly serves onDaly’s biography, the board of directors of biopharmaceutical companies Acadia Pharmaceuticals Inc., argenx SE, Bellicum Pharmaceuticals, Inc. and Madrigal Pharmaceuticals, Inc. Mr. Daly earned his B.S. in Pharmacy and M.B.A. from the University at Buffalo, The State University of New York.
The Nominating and Corporate Governance Committee believes thatMr. Daly has the relevant background in the following areas which the committee believes are important to service on the Company’s Board of Directors: (i) pharma business leadership and operations and (ii) international business. Mr. Daly’s extensive commercial, business development and leadership experience at biopharmaceutical companies including his involvement in the successful launch of pharmaceutical products, management of large commercial operations and his experience serving on the board of directors at other biopharmaceutical companies provides valuable experience and perspective to our Board, of Directors, leading the Nominating and Corporate Governance Committee to determine that Mr. Daly should serve as one of our directors.





Directors Continuing in Office Until the 2022 Annual Meeting
Jeffrey W. Henderson. Mr. Henderson has served as President of JWH Consulting LLC, a business advisory firm primarily focused on healthcare since January 2018. Mr. Henderson provides our Board of Directors with a wealth of corporate leadership experience, particularly in corporate finance, having served as the Chief Financial Officer of Cardinal Health, Inc. from May 2005 to November 2014. As Cardinal Health’s Chief Financial Officer, Mr. Henderson led various departments within the company, including finance, information technology and global shared services. He also had operational responsibility for Cardinal’s business in Canada and China. From November 2014 to his retirement from Cardinal Health in August 2015, Mr. Henderson served in an executive capacity assisting in the transition of his responsibilities as Chief Financial Officer. Prior to joining Cardinal Health, Mr. Henderson held various senior management positions at Eli Lilly and Company from 1998 to 2005, including President and General Manager, Eli Lilly Canada, Inc., Vice President and Corporate Controller and Vice President and Corporate Treasurer. From 1988 to 1998, Mr. Henderson held various senior management positions at General Motors Corporation including serving as Chief Financial Officer at IBC Vehicles Limited and as Regional Treasurer at GM’s Asia-Pacific Regional Treasury Center. He currently serves on the board of directors of Becton Dickinson and Company, a medical technology company, Fibrogen, Inc., a biotechnology company, and Qualcomm, Inc., a wireless communications company. He holds a B.S. degree in electrical engineering from Kettering University and a M.B.A. from Harvard Graduate School of Business Administration.
The Nominating and Corporate Governance Committee believes Mr. Henderson’s extensive experience serving in executive leadership positions, including as Chief Financial Officer, with a large publicly-traded healthcare corporation, combined with his business acumen and judgment, including his qualifications as an audit committee financial expert, provide our Board of Directors with valuable financial, strategic and operational expertise and leadership skills, leading the Nominating and Corporate Governance Committee to determine that Mr. Henderson should serve as one of our directors.
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Connie L. Matsui. Ms. Matsui brings to our Board over 18 years of general management experience in the biotechnology industry. She retired from Biogen Idec Inc. in January 2009 as the Executive Vice President, Knowledge and Innovation Networks. She served as an Executive Committee member at both Biogen Idec and IDEC Pharmaceuticals, a predecessor of Biogen Idec. Among the major roles she played after joining IDEC Pharmaceuticals in November 1992 were: Senior Vice President, overseeing investor relations, corporate communications, human resources, project management and strategic planning; Collaboration Chair for the late stage development and commercialization of rituximab (tradenames: Rituxan® and MabThera®) in partnership with Roche and Genentech; and Project Leader for Zevalin®, the first radioimmunotherapy approved by the U.S. FDA. Prior to entering the biotechnology industry, Ms. Matsui worked for Wells Fargo Bank in general management, marketing and human resources. Ms. Matsui has been active on a number of not-for-profit boards and served as National President/Board Chair of the Girl Scouts of the USA from 1999 to 2002. Ms. Matsui serves on the board of directors biopharmaceutical companies Artelo Biosciences, Inc. and Sutro Biopharma, Inc. Ms. Matsui earned B.A. and M.B.A. degrees from Stanford University.
The Nominating and Corporate Governance Committee believes that Ms. Matsui’s operational experience, including her extensive knowledge of the biotechnology industry, her service in other public company management teams and her prior business experience, combined with her business acumen and judgment, provide our Board of Directors with valuable management and operational expertise and leadership skills, leading the Nominating and Corporate Governance Committee to determine that Ms. Matsui should serve as one of our directors.
Helen I. Torley, M.B. Ch.B., M.R.C.P. Dr. Torley brings to our company extensive commercial and business experience as well as an extensive knowledge of the biotechnology industry. Dr. Torley joined Halozyme in January 2014 as President and Chief Executive Officer. Throughout her career, Dr. Torley has led several successful product launches, including Kyprolis®, Prolia®, Sensipar®, and Miacalcin®. Prior to joining Halozyme, Dr. Torley served as Executive Vice President and Chief Commercial Officer for Onyx Pharmaceuticals from August 2011 to December 2013 overseeing the collaboration with Bayer on Nexavar® and Stivarga® and the U.S. launch of Kyprolis. She was responsible for the development of Onyx’s commercial capabilities in ex-US markets and in particular, in Europe. Prior to Onyx, Dr. Torley spent 10 years in management positions at Amgen Inc., most recently serving


as Vice President and General Manager of the US Nephrology Business Unit from 2003 to 2009 and the U.S. Bone Health Business Unit from 2009 to 2011. From 1997 to 2002, she held various senior management positions at Bristol-Myers Squibb, including Regional Vice President of Cardiovascular and Metabolic Sales and Head of Cardiovascular Global Marketing. She began her career at Sandoz/Novartis, where she ultimately served as Vice President of Medical Affairs, developing and conducting post-marketing clinical studies across all therapeutic areas, including oncology. Dr. Torley serves on the board of directors of Quest Diagnostics Incorporated, a diagnostic information services company. Within the past five years, Dr. Torley served on the board of directors of Relypsa, Inc., a biopharmaceutical company. Before joining the industry, Dr. Torley was in medical practice as a senior registrar in rheumatology at the Royal Infirmary in Glasgow, Scotland. Dr. Torley received her Bachelor of Medicine and Bachelor of Surgery degrees (M.B. Ch.B.) from the University of Glasgow and is a Member of the Royal College of Physicians (M.R.C.P).
The Nominating and Corporate Governance Committee believes that Dr. Torley’s extensive commercial and operational experience, including successful launches of products, and her deep knowledge of the biotechnology industry and the competitive environment, and her service as our Chief Executive Officer, combined with her business acumen and judgment, provide our Board of Directors with valuable commercial and operational expertise and leadership skills, leading the Nominating and Corporate Governance Committee to determine that Dr. Torley should serve as one of our directors.








CORPORATE GOVERNANCE
Director Independence
The Board of Directors (or “Board”) has determined that, other than Dr. Torley, each of the members of the Board of Directors is an independent director within the meaning set forth under applicable rules of the NASDAQ Stock Market. Dr. Torley does not meet the requirements for director independence because she serves as the President and Chief Executive Officer of Halozyme.
Board Leadership
In 2005, theThe Board has separated the Chief Executive Officer and Board Chair positions to: (i) provide a stronger corporate governance structure; (ii) improve overall Board effectiveness; and (iii) enhance communication between management and the Board. Ms. Matsui began serving as the non-employee Chair of the Board of Directors in February 2016.
Board Tenure
boardtenurea.jpg
Executive Sessions
Our independent directors generally meet in executive session without management present each time the Board holds its regularly scheduled meetings. The Chair of the Board of Directors, acts as the presiding director for such executive sessions of independent directors.
Board Meetings and Committees
The Board of Directors held sixten meetings during the fiscal year ended December 31, 2019.2021. The Board of Directors has three standing committees: (i) Audit Committee; (ii) Compensation Committee; and (iii) Nominating and Corporate Governance Committee. During the last fiscal year, each director attended at least 75% of the total number of meetings of the Board and the committees of the Board on which such director served during that period. Our standing committees are currently comprised of the following directors:
NameAudit Committee
Compensation

 Committee
Nominating / Corporate

Governance Committee
Jean-Pierre Bizzari, M.D.
X
X
Bernadette ConnaughtonXXChair
James M. DalyXX
Jeffrey W. HendersonChairX
Kenneth J. KelleyXChair
Connie L. MatsuiChair
Matthew L. PosardX
XChair
Moni Miyashita
Helen I. Torley, M.B.M.D. Ch.B., M.R.C.P.
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________________
Audit Committee
The current members of the Audit Committee are Jeffrey W. Henderson (Chair), Bernadette Connaughton, Kenneth J. KelleyJames M. Daly and Mathew L. Posard. All members of the Audit Committee satisfy the independence requirements set forth under the applicable rules of the NASDAQ Stock Market and Rule 10A-3 of the Exchange Act, and each of them is able to read and fundamentally understand financial statements. Mr. Henderson is an “audit committee financial expert,” as defined in the rules of the Securities and Exchange Commission. The Audit Committee operates under a written charter that is available on our website at: www.halozyme.com. The primary purpose of the Audit Committee is to oversee our accounting and financial reporting processes and the functions of the Audit Committee include retaining our independent registered public accounting firm, reviewing its independence, reviewing and approving the planned scope of its annual audit, reviewing and approving any fee arrangements with our independent registered public accounting firm, overseeing its audit work, reviewing and pre-approving any non-audit services that may be performed by the independent registered public accounting firm, reviewing the adequacy of our accounting and


financial controls, reviewing our critical accounting policies and reviewing and approving any related party transactions. The Audit Committee held fivesix meetings during the fiscal year ended December 31, 2019.2021.
Additional information regarding the Audit Committee is set forth in the Report of the Audit Committee contained in this Proxy Statement.
Compensation Committee
The current members of the Compensation Committee are Connie L. MatsuiBernadette Connaughton (Chair), Jeffrey W. Henderson and Jean-Pierre Bizzari, Bernadette Connaughton and Jeffrey W. Henderson.M.D. All members of the Compensation Committee satisfy the independence requirements set forth under the applicable rules of the NASDAQ Stock Market, qualify as non-employee directors as defined in Rule 16b-3 under the Securities Exchange Act, and as outside directors within the meaning of Section 162(m) of the Internal Revenue Code of 1986, as amended. The Compensation Committee operates under a written charter that is available on our website at: www.halozyme.com. The primary purpose of the Compensation Committee is to discharge the Board’s responsibilities relating to compensation and benefits of our executive officers. More specifically, the Compensation Committee reviews and approves the salary and bonus earned by the Chief Executive Officer and other executive officers; approves equity awards to executive officers; approves employment and severance agreements of executive officers; and reviews the compensation of non-employee directors for service on the Board of Directors and its committees. The Compensation Committee held five meetings during the fiscal year ended December 31, 2019.2021.
Nominating and Corporate Governance Committee
The current members of the Nominating and Corporate Governance Committee are Kenneth J. KelleyMatthew L. Posard (Chair), Jean-Pierre Bizzari, M.D, and James M. Daly and Matthew L. Posard.Daly. All members of the Nominating and Corporate Governance Committee satisfy the independence requirements set forth under the applicable rules of the NASDAQ Stock Market. The Nominating and Corporate Governance Committee operates under a written charter that is available on our website at: www.halozyme.com. The primary responsibilities of the Nominating and Corporate Governance Committee are to (i) identify individuals qualified to become Board members; (ii) select, or recommend to the Board, director nominees for each election of directors; (iii) develop and recommend to the Board criteria for selecting qualified director candidates; (iv) consider committee member qualifications, appointment and removal; (v) recommend applicable corporate governance principles, codes of conduct and compliance mechanisms, and (vi) provide oversight in the evaluation of the Board and each committee. The Nominating and Corporate Governance Committee held fourfive meetings during the fiscal year ended December 31, 2019.2021.
With respect to Board membership, the Nominating and Corporate Governance Committee’s goal is to assemble a Board of Directors that brings a variety of perspectives and skills derived from high quality business and professional experience. There are no stated minimum criteria for director nominees, but the Nominating and Corporate Governance Committee believes that at least one member of the Board should meet the criteria for an “audit committee financial expert” as defined by SEC rules, and that a majority of the members of the Board should meet the definition of “independent director” under the applicable rules of the NASDAQ Stock Market. The Nominating and Corporate Governance Committee also believes it is appropriate for at least one key member of management to participate as a member of the Board.
While we do not have a formal diversity policy, ourThe Halozyme Board of Directors believes that our Board should have diversity of knowledge base, professional experience and skills, and actively seeks director candidates who bringsbring diversity of age, gender, nationality, race, ethnicity and sexual orientation. When considering whether to recommend any candidate for inclusion in the Board’s slate of recommended director nominees, including candidates recommended by our stockholders, the Nominating and Corporate Governance Committee will review the candidate’s integrity, business acumen, age, experience, commitment, diligence, conflicts of interest, existing time commitments and the ability to act in the interests of all stockholders. Once a potential qualified candidate is identified, multiple members of the Nominating and Corporate Governance Committee will interview that candidate. The committee may also ask the candidate to meet with non-committee members of the Board and/or members of management and,
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if the committee believes a candidate would be a valuable addition to the Board, it will recommend that candidate to the full Board.
Pursuant to the terms of its charter and our Corporate Governance guidelines,Guidelines, the Nominating and Corporate Governance Committee will consider qualified director candidates suggested by our stockholders. Stockholders may recommend individuals for the Nominating and Corporate Governance Committee to consider as potential director candidates by submitting the candidate’s


name, contact information and biographical information in writing to the “Halozyme Nominating and Corporate Governance Committee” c/o Corporate Secretary, 11388 Sorrento Valley Road, San Diego, California 92121. The biographical information and background materials of any such candidate will be forwarded to the Nominating and Corporate Governance Committee for its review and consideration. The committee’s review process for candidates identified by our stockholders is essentially identical to the review process for candidates identified by the committee. In addition to the process discussed above regarding the consideration of the Nominating and Corporate Governance Committee of candidates suggested by our stockholders, our Bylaws contain provisions that address the process by which a stockholder may nominate an individual to stand for election to our Board at our Annual Meeting of Stockholders.
Risk Management
Our Board is responsible for reviewing and assessing business enterprise risk and other major risks facing the Company, and evaluating management’s approach to addressing such risks. Periodically, our Board reviews key risks facing the Company, plans for addressing these risks and the Company’s risk management practices overall. In connection with these reviews, our Board members rely on information from external sources as well as on their individual experiences identifying and managing business enterprise risk for other entities both within and outside of our industry. In addition, the committees of our Board consider and address risk as they perform their respective committee responsibilities. For example, financial risks are overseen by our Audit Committee and our Compensation Committee periodically reviews the most important enterprise risks to ensure that our compensation programs do not encourage excessive risk-taking. All committees report to the full Board as appropriate, including when a matter rises to the level of a material or enterprise risk.
Our senior management team is responsible for day-to-day risk management and regularly reports on risks to our full Board or a relevant committee. Our legal, finance and regulatory areas serve as the primary monitoring and evaluation function for company-wide policies and procedures, and manage the day-to-day oversight of the risk management strategy for our business. This oversight includes identifying, evaluating, and addressing potential risks that may exist at the enterprise, strategic, financial, operational, compliance and reporting levels.
We believe the division of risk management responsibilities described above is an effective approach for identifying and addressing the risks facing our Company, and that the leadership structure of our Board is effective in implementing this approach.
ESG and Corporate Responsibility
Halozyme continues to build a sustainable, environmentally conscious business while fulfilling our mission of bringing disruptive solutions that can significantly improve patient experiences and outcomes for emerging and established therapies. We are driven by our mission and dedicated to our sustainability efforts across our entire ecosystem internally and externally.
Please see the discussion under the heading “Human Capital Management” in the Business section of our Annual Report on Form 10-K (which accompanies this Proxy Statement) for additional information on our human capital priorities and programs. We also recognize that certain stakeholders (such as customers, employees and non-governmental organizations) as well as some stockholders may be interested in more detailed information about our ESG programs and sustainability efforts. We encourage you to review the information available on our website at www.halozyme.com under the section titled “Responsibility” where our 2021 Environmental, Social & Governance Report can be accessed. Information on our website is not part of this Proxy Statement.
Cybersecurity
Our corporate Enterprise Risk Management program, which includes information technology and cybersecurity risk, is reviewed quarterly by the CEO and Halozyme Leadership Team, and annually by the Halozyme Board of Directors. Additionally, Halozyme’s CEO is briefed quarterly and the Audit Committee is briefed annually or as determined by CIO and CEO, on our cybersecurity program. Our cybersecurity strategy is based on four fundamental areas: policy, procedure, people and technology. Halozyme maintains policies and procedures that describe our employees’ responsibilities for accessing computerized systems, handling data and information, and reporting cybersecurity events in a timely manner. The Board of Directors receives educational updates from outside experts on key emergent topics. All employees and contractors are required to complete formal training on these policies. Halozyme has a well-defined and proven Business Continuity Plan (BCP). The IT
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Disaster Recovery Plan and the IT Incident Response Plan, which are standalone components of Halozyme’s BCP, provide the framework and guidance to manage risk.
Communications with Directors    
Stockholders may communicate with any and all directors by transmitting correspondence by mail addressed as follows: “Halozyme Board of Directors” c/o Corporate Secretary, 11388 Sorrento Valley Road, San Diego, California 92121. The Corporate Secretary will transmit as soon as practicable such communications to the identified director addressee(s), unless there are safety or security concerns that mitigate against further transmission of the communication as determined by the Corporate Secretary.
Director Attendance at Annual Meetings
Our Corporate Governance Guidelines state that all directors shall make every effort to attend the Company’s Annual Meeting of Stockholders. EightAll seven of our then-serving directors attended our Annual Meeting of Stockholders in 2019.2021.
Code of Conduct and Ethics and Corporate Governance Guidelines
The Board has adopted a Code of Conduct and Ethics that applies to all of our employees, officers and directors. The Board has also adopted Corporate Governance Guidelines. Copies of these documents are available on our website at: www.halozyme.com. Amendments to or waivers of our Code of Conduct and Ethics granted to any of our directors or executive officers will be published promptly within four business days on our website, www.halozyme.com. Please note that the information on our website is not incorporated by reference in this Proxy Statement.
Compensation Committee Interlocks and Insider Participation
None of the directors who served on the Compensation Committee during 20192021 has ever been an officer or employee of ours or had a relationship in 20192021 requiring disclosure under applicable SEC regulations. None of our executive officers currently serves, or served during 2019,2021, on the compensation committee or board of directors of any other entity that has an executive officer serving as a member of our Board of Directors or Compensation Committee.

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PROPOSAL NO. 2
ADVISORY (NON-BINDING) VOTE
ON EXECUTIVE COMPENSATION (SAY-ON-PAY)
Background
The advisory vote on executive compensation is a non-binding vote on the compensation of our Named Executive Officers, as described in the Compensation Discussion and Analysis section, the tabular disclosure regarding such compensation, and the accompanying narrative disclosure, set forth in this Proxy Statement. Please read the Executive Compensation Discussion and AnalysisRelated Information section of this Proxy Statement for a detailed discussion about our executive compensation programs, including information about the fiscal year 20192021 compensation of our Named Executive Officers.
The advisory vote on executive compensation is not a vote on our general compensation policies, the compensation of our Board of Directors, or our compensation policies as they relate to risk management. The Dodd-Frank Wall Street Reform and Consumer Protection Act requires that we hold the advisory vote on executive compensation at least once every three years. Upon the recommendation of our stockholders at our 2017 Annual Meeting of Stockholders, our Board of Directors determined that we will hold the advisory vote on executive compensation annually until the next required non-binding stockholder advisory vote on the frequency of future non-binding stockholder non-binding advisory votes on the compensation of our Named Executive Officers which will occur no later than our 2023 Annual Meeting of Stockholders.
We have many compensation practices that ensure consistent leadership, decision-making and actions without taking inappropriate or unnecessary risks. These compensation practices are discussed in detail in the Compensation Discussion and Analysis section of this Proxy Statement and have the following objectives:
Properly align the interests of our stockholders with those of our executive leadership team;
Reward actions and achievements that are consistent with the short- and long-term goals of Halozyme’s business strategy; and
Remain competitive to attract, retain and motivate employees with relevant experience and skills needed to achieve our business goals.
The vote solicited by this Proposal No. 2 is advisory, and therefore is not binding on the Company, our Board of Directors or our Compensation Committee, nor will its outcome require the Company, our Board of Directors or our Compensation Committee to take any action. Moreover, the outcome of the vote will not be construed as overruling any decision by the Company, the Board of Directors or the Compensation Committee.
Furthermore, because this non-binding, advisory resolution primarily relates to the compensation of our Named Executive Officers that has already been paid or contractually committed, there is generally no opportunity for us to revisit these past decisions. However, our Board of Directors, including our Compensation Committee, values the opinions of our stockholders and, to the extent there is any significant vote against the Named Executive Officer compensation as disclosed in this Proxy Statement, we will consider our stockholders’ concerns and evaluate what actions, if any, may be appropriate to address those concerns. 
Stockholders will be asked at the Annual Meeting to approve the following resolution pursuant to this Proposal No. 2:
RESOLVED, that the stockholders of Halozyme Therapeutics, Inc. approve, on an advisory basis, the compensation of the Company’s Named Executive Officers, disclosed pursuant to Item 402 of Regulation S-K in the Company’s Definitive Proxy Statement for the 20202022 Annual Meeting of Stockholders.
Vote Required
Approval of this resolution requires the affirmative vote of a majority in voting power of the shares present in person or represented by proxy at the meeting and entitled to vote on the matter. Abstentions will be treated as votes “against” the proposal. Broker non-votes will have no effect on the outcome of the vote.
Recommendation
The Board of Directors believes that the compensation of our Named Executive Officers, as described in the Compensation Discussion and Analysis and the tabular disclosures and accompanying narrative disclosures under the heading “Executive Compensation and Related Information” is appropriate for the reasons stated above. Therefore, the Board of Directors unanimously recommends a vote “FOR” approval of the compensation for our Named Executive Officers.

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PROPOSAL NO. 3
RATIFICATION OF SELECTION OF
INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
The Audit Committee of the Board of Directors of Halozyme has selected Ernst & Young LLP as the independent registered public accounting firm to audit the consolidated financial statements of Halozyme for the fiscal year ending December 31, 2020.2022. Ernst & Young LLP has acted in such capacity since its appointment on June 28, 2006. A representative of Ernst & Young LLP is expected to be present at the Annual Meeting of Stockholders, with the opportunity to make a statement if the representative desires to do so, and is expected to be available to respond to appropriate questions.
Stockholder ratification of the selection of Ernst & Young LLP as our independent registered public accounting firm is not required by our Bylaws or otherwise. However, the Board of Directors is submitting the selection of Ernst & Young LLP to the stockholders for ratification as a matter of good corporate practice. If the stockholders fail to ratify the selection, the Audit Committee will reconsider whether or not to retain that firm. Even if the selection is ratified, the Audit Committee in its discretion may appoint a different independent registered public accounting firm at any time during the year if it determines that such a change would be in the best interests of the Company and its stockholders.
Vote Required
The affirmative vote of a majority in voting power of the shares present in person or represented by proxy at the meeting and entitled to vote on the matter shall ratify the selection of Ernst & Young LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2020.2022. Abstentions will be treated as votes “against” the proposal. Broker non-votes will have no effect on the outcome of the vote.
Board of Directors Recommendation
The Board of Directors unanimously recommends a vote “FOR” the ratification of the selection of Ernst & Young LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2020.2022.
PRINCIPAL ACCOUNTING FEES AND SERVICES
The following table sets forth the aggregate fees billed to Halozyme for the fiscal years ended December 31, 20192021 and 20182020 by Ernst & Young LLP:
  Fiscal 2019 Fiscal 2018
Audit Fees(1) 
$892,492
 
$857,465
Tax Fees(2) 61,230
 64,192
All Other Fees(3) 
 3,460
Total 
$953,722
 
$925,117
Fiscal 2021Fiscal 2020
Audit Fees (1)
$983,451 $806,350 
Tax Fees (2)
55,522 275,030 
All Other Fees (3)
2,665 33,918 
Total$1,041,638 $1,115,298 
________________
(1)Audit Fees consist of fees billed for professional services rendered for the audit of the Company’s consolidated annual financial statements, including the audit of internal control over financial reporting and review of the interim consolidated financial statements included in quarterly reports and services that are normally provided by our independent registered public accounting firm in connection with statutory and regulatory filings or engagements.
(2)Tax Fees consist of fees billed for professional services rendered for tax compliance and tax advice.
(3)All Other Fees consist of fees for products and services other than the services reported above.

(1)Audit Fees consist of fees billed for professional services rendered for the audit of the Company’s consolidated annual financial statements, including the audit of internal control over financial reporting and review of the interim consolidated financial statements included in quarterly reports and services that are normally provided by our independent registered public accounting firm in connection with statutory and regulatory filings or engagements.

(2)Tax Fees consist of fees billed for professional services rendered for tax compliance and tax advice.
(3)All Other Fees consist of fees for products and services other than the services reported above.

The Audit Committee’s policy is to pre-approve all audit and permissible non-audit services provided by our independent registered public accounting firm. These services may include audit services, audit-related services, tax services and other services. Pre-approval is generally provided for up to one year and any pre-approval is detailed as to the particular service or category of services. The independent registered public accounting firm and management are required to periodically report to the Audit Committee regarding the extent of services provided by the independent registered public accounting firm in accordance with this pre-approval policy. The Chair of the Audit Committee is also authorized, pursuant to delegated authority, to pre-approve additional services on a case-by-case basis, provided that such approvals are communicated to the full Audit Committee at its next meeting.

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REPORT OF THE AUDIT COMMITTEE
The Audit Committee oversees the Company’s financial reporting process on behalf of the Board of Directors.Directors and is comprised solely of independent directors as defined by the Nasdaq listing standards and Rule 10A-3 of the Securities Exchange Act of 1934. The Audit Committee is governed by a charter which describes in greater detail the full responsibilities of the Audit Committee. The Company’s management has the primary responsibility for the consolidated financial statements, for maintaining effective internal control over financial reporting, and for assessing the effectiveness of internal control over financial reporting. In fulfilling its oversight responsibilities, the Audit Committee reviewed and discussedreviews the audited consolidated financial statements, internal control over financial reporting, audit matters and reports from management. In connection with these reviews, the Audit Committee meets with management and the related scheduleindependent registered public accounting firm (Ernst & Young LLP) at least once each quarter. These meetings include, whenever appropriate, executive sessions in which the Annual ReportAudit Committee meets separately with Companythe independent registered public accounting firm, internal auditors, management including a discussion of the quality, not just the acceptability, of the accounting principles; the reasonableness of significant judgments;personnel and the clarity of disclosures in the financial statements.
The Committee is governed by a charter. The Committee held five meetings during fiscal year 2019. The Committee is comprised solely of independent directors as defined by the Nasdaq listing standards and Rule 10A-3 of the Securities Exchange Act of 1934.legal counsel. The meetings of the Audit Committee are designed to facilitate and encourage communication among the Audit Committee, the Company, the Company’s internal audit function and the Company’sindependent registered public accounting firm. The Audit Committee is directly and solely responsible for the appointment, compensation, retention, and oversight of the independent registered public accounting firm. The Audit Committee regularly considers the independence, qualifications, audit and non-audit fees and services, and performance of the independent registered public accounting firm.
The Audit Committee discussed with the Company’s independent registered public accounting firm the overall scope and plans for their respective audits. The Committee meets with the independent registered public accounting firm, with and without management present, to discuss the results of their examinations; their evaluations of the Company’s internal control, including internal control over financial reporting; and the overall quality of the Company’s financial reporting.
The Committeehas reviewed and discussed with the independent registered public accounting firm, which is responsible for expressing an opinion on the conformity of thosethe audited consolidated financial statements and related schedule with U.S. generally accepted accounting principles, its judgments as to the quality, not just the acceptability, of the Company’s accounting principles and such other matters as are required to be discussed by the standardsapplicable requirements of the Public Company Accounting Oversight Board (United States) (PCAOB) the rules ofand the Securities and Exchange Commission, and other applicable regulations. In addition, the Audit Committee has receivedreviewed and discussed with Ernst & Young LLP matters related to its independence, including a review of non-audit services and the written disclosures and the letter from Ernst & Young LLP to the Audit Committee required by the PCAOB regarding its communications with the Audit Committee concerning Ernst & Young LLP’s independence. The Audit Committee concluded that Ernst & Young LLP is independent from the Company and its management.
The Audit Committee discussed with the Company’s independent registered public accounting firm the overall scope and plans for their respective audits. The Audit Committee has met the independent registered public accounting firm, required bywith and without management present, to discuss the PCAOB regardingresults of their examinations; their evaluations of the firm’s communications withCompany’s internal control, including internal control over financial reporting; the Committee concerningcritical audit matter addressed during the firm’s independence, has discussed with the independent registered public accounting firm the firm’s independence from Company managementaudit and the Company and consideredoverall quality of the compatibility of non-audit services with the firm’s independence.Company’s financial reporting.
The Committee also reviewed and discussed with management and the independent registered public accounting firm the Company’s audited consolidated financial statements and related schedule for the year ended December 31, 2019 and the results of management’s assessment of the effectiveness of the Company’s internal control over financial reporting and the independent registered public accounting firm’s audit of internal control over financial reporting.reporting for the year ended December 31, 2021.
In reliance on the reviews and discussions referred to above, the Audit Committee recommended to the Board of Directors, and the Board of Directors has approved, that the audited consolidated financial statements and related schedule and management’s assessment of the effectiveness of the Company’s internal control over financial reporting be included in the Annual Report on Form 10-K for the year ended December 31, 20192021 filed by the Company with the Securities and Exchange Commission.
AUDIT COMMITTEE
Jeffrey W. Henderson (Chair)
Bernadette Connaughton                            James M. Daly
Kenneth J. Kelley
Matthew L. Posard
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EXECUTIVE COMPENSATION AND RELATED INFORMATION
COMPENSATION DISCUSSION AND ANALYSIS
Executive Summary
The Compensation Committee oversees the compensation program for the Company’s executive officers. In this role, the Compensation Committee reviews and approves annually all compensation decisions relating to our Namedexecutive officers listed in the “Summary Compensation Table” below (referred to in this proxy statement as our “Named Executive Officers (“NEOs”Officers” or “NEOs”).
Halozyme’sOur executive compensation program ties a substantial portion of each executive’s overall compensation to the achievement of key strategic, financial and operational goals and aligns the interests of executive officers with stockholders by annually awarding bothlong-term equity-based incentives, in the form of time-vesting restricted stock units (“RSUs”), performance-vesting stock units (“PSUs”) and stock options. Consistent with this approach, the compensation of our NEOs for 20192021 featured:
cash payouts under our annual cash bonus program ranging from 104100 percent and 124.8121.6 percent of target, reflective of theour strong financial and operating performance of Halozyme as well as strong individual performance,
base salary, target bonus opportunity, and long-term equity-based grant values consistent with executives at similarly situated biopharmaceutical companies,
a compensation package more heavily weighted toward long-term equity-based incentive compensation than salary and shorter-term annual cash incentives in order to emphasize the focus on Halozyme’sour long-term performance and stockholder value,
long-term equity-based incentives that were heavily weighted toward performance – in addition to the value of all the awards being dependent on our stock price, the awards granted in 2021 included PSUs which are subject to performance-based vesting conditions and stock options which have value only if our stock price increases after the date of grant of the awards,
stock ownership and stock retention guidelines, encouraging executives to maintain a meaningful ownership position in the Company, focus on Halozyme’sour long-term performance and discourage unreasonable risk-taking,
certain compensation elements subject toa recoupment (or “claw back”) policy covering certain compensation elements in the event of an accounting restatement due to material noncompliance with any financial reporting requirements,
a policy not to include tax gross-ups in ongoing compensation arrangements,
double-triggerno “single trigger” provisions in all executive and employee change-in-control agreements and arrangements (i.e., payout or vesting is not triggered automatically upon a change-in-control), and
no ongoing perquisites other than selective relocation reimbursements.material perquisites.
Management has a practice of periodically solicitingHalozyme regularly solicits feedback on Halozyme’sour executive compensation program from institutionalour stockholders. Specific feedback from stockholders is discussed withand considered by the Compensation Committee and taken into account as futureexecutive compensation decisions are made. For example, theThe Compensation Committee has taken the following actions since 2017 as a result ofin response to feedback from stockholders:
enhanced disclosure in the Compensation Discussion and Analysis (“CD&A”) regarding the annual bonus plan design, and
modified the peer group used for compensation comparisons to include companies that are similar to Halozyme with respect to its business model, and
continued discussions around future long-term incentive (“LTI”) plan design.design, including the introduction of the PSUs as part of the mix of annual LTI awards for our executive officers in 2021.
20192021 Business Highlights
Halozyme’s operating performance throughout 2021 was marked by strong financial execution and critical new developments with ENHANZE® collaboration partners. Among the significant achievements for Halozyme successfully completedduring 2021 are the following:
Record revenues of $443.3 million, which increased 66% from 2020 revenues of $267.6 million;
Revenues from royalties more than doubled to $203.9 million driven by continued strong sales from partnered products utilizing our ENHANZE® technology and specifically the subcutaneous forms of Johnson & Johnson’s DARZALEX® (daratumumab) and Roche’s Phesgo® (pertuzumab/trastuzumab/hyaluronidase-zzxf);
Three additional U.S. FDA approvals for Janssen Biotech, Inc.’s DARZALEX FASPRO® (daratumumab hyaluronidase human- fihj) utilizing Halozyme’s ENHANZE® technology for use:
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in combination with bortezomib, cyclophosphamide and dexamethasone (D-VCd) for the treatment of adult patients with newly diagnosed light chain (AL) amyloidosis, the first and only FDA-approved treatment for patients with this rare and serious blood disorder;
in combination with pomalidomide and dexamethasone (Pd) for the treatment of adult patients with multiple myeloma who have received at least one prior line of therapy, including lenalidomide and a transitionproteasome inhibitor; and
in combination with Kyprolis® (carfilzomib) and dexamethasone (Kd) for the treatment of adult patients with relapsed or refractory multiple myeloma who have received one to focus its business solelythree prior lines of therapy;
Two European Marketing Authorizations for Janssen Pharmaceutical Companies of Johnson & Johnson’s subcutaneous form of DARZALEX® utilizing Halozyme’s ENHANZE® technology for use:
in combination with other therapies to treat adults with newly diagnosed systemic light-chain (AL) amyloidosis; and
in combination with other therapies to treat adults with multiple myeloma (MM) who have received one prior therapy containing a proteasome inhibitor and lenalidomide and were lenalidomide refractory, or who have received at least two prior therapies that included lenalidomide and a proteasome inhibitor, and have demonstrated disease progression on itsor after the last therapy.
A new collaboration and license agreement with ViiV Healthcare - the global specialist HIV company majority owned by GlaxoSmithKline plc, granting ViiV exclusive access to our ENHANZE® drug delivery technology following the announcement in November 2019for subcutaneous formulation of negative results of its HALO-301 Phase 3 clinical study. As a result, the Company halted its proprietary drug development activities and initiated a restructuring to position the Company for success and growthmedicines addressing specific targets used in the future. Duringtreatment and prevention of HIV, resulting in an upfront milestone payment of $40 million to Halozyme. This expands our total number of collaboration and licensing agreements to 11;
Initiation by partners of 10 new clinical studies, broadening and advancing our pipeline;
Issuing $805 million aggregate principal amount of convertible senior notes due 2027 paying interest semi-annually in arrears at an annual rate of 0.25% for general corporate purposes, repurchases of the entire year, but particularly during this restructuring process, the Company operated efficientlyCompany’s common stock from time to time, working capital, capital expenditures, potential acquisitions and effectively with a focused and cohesive leadership team. Specifically, during 2019 Halozyme accomplished:strategic transactions;
Strategic Actions to Reposition Focus on ENHANZE: Executed several important actions to immediately reposition the company, including:


initiated a corporate restructuring that will enable the Company to become sustainably profitable beginning in the second quarterCompletion of 2020. The restructuring included a headcount reduction of 55%, or approximately 160 positions, which was substantially completed in January 2020,
commenced execution of a board-approved $550 million three-year share repurchase plan approved by Halozyme’s Board of Directors in November 2019, and initiation of a new share repurchase program, of which authorizes the Company completed $200to purchase up to $750 million worth of share repurchases prior to the end of the first quarter of 2020,
successfully completed a $460 million offering of convertible senior notes due 2024 to recapitalize the CompanyCompany's outstanding common stock over three years; and facilitate an immediate return of capital to investors via share repurchases, and
implemented cost reductions expected to result in annualized corporate operating expenses, excluding cost of goods sold, of $65 million to $75 million upon completion of the restructuring, which is anticipated by the fourth quarter of 2020.
In addition to these strategic actions, we made significant progress with our ENHANZE® drug delivery technology, including:
supported our partners in advancing five new products in combinationIncreased focus on corporate responsibility with the ENHANZE technology to the clinicintroduction of a new corporate website highlighting Halozyme’s commitment in 2019, including initiationsthis area, and publication of Phase 1 studies from argenx, Roche, Bristol-Myers Squibb,our 2021 Environmental, Social and an existing partner that remains undisclosed,
announced that Roche selected an additional target for development,
supported regulatory filings by our partner Janssen to the U.S. Food and Drug Administration and European Medicines Agency in July 2019 for the subcutaneous formulation of Darzalex® (daratumumab) utilizing ENHANZE,
announced positive phase 3 results were achieved by our partner, Genentech, a member of the Roche Group, in its Phase 3 FeDeriCa study and completion of regulatory filings in the United States and EU in the first quarter of 2020. The FeDeriCa study investigated a fixed-dose combination of pertuzumab (Perjeta®) and trastuzumab (Herceptin®) for subcutaneous administration using Halozyme's ENHANZE drug delivery technology in combination with intravenous chemotherapy.
entered into an agreement with argenx, a biotechnology company, in February 2019 for the right to develop and commercialize one exclusive target, the human neonatal Fc receptor FcRn, which is the target argenx's lead asset efgartigimod (ARGX-113) is directed against. Subsequently in May 2019, argenx nominated a second target to be studied using ENHANZE technology, a human complement factor C2 associated with the product candidate ARGX-117, which is being developed to treat severe autoimmune diseases, triggering a $10.0 million payment,
announced in February 2019 that Genentech, a member of the Roche Group, received approval from the FDA for Herceptin Hylecta™ (trastuzumab and hyaluronidase-oysk), a co-formulation of trastuzumab and rHuPH20 marketed as Herceptin SC outside of the U.S. Herceptin Hylecta is approved for the treatment of certain people with HER2-positive early breast cancer.
Financial Results: Revenue in 2019 increased 29% from 2018 to $196.0 million as expected driven by an increase in our collaboration revenue, and an increase in bulk rHuPH20 sales to our partners offset by a slight decline in royalties. The Company ended 2019 with $421.3 million in cash and marketable securities, compared to $354.5 million at the end of 2018.Governance (ESG) Report.
20192021 CEO Compensation
In 2019,2021, the annualized total target annual cash compensation for our Chief Executive Officer (“CEO”), Dr. Helen I. Torley, was $1,331,750$1,494,398 ($761,000830,221 in base salary plus $570,750$664,177 in target bonus opportunity). Dr. Torley’s base salary was increased for 20192021 by 5.0%4.9% as a result of the Compensation Committee’s assessment of her contribution to Halozyme’s performance during 20182020 and its review of base salary paid to other peer group CEOs (based on proxy data compiled from Equilar’s executive compensation benchmarking platform) relative to our pay philosophy.CEOs. Dr. Torley’s target bonus opportunity for 20192021 (assuming achievement of the corporate goals at 100%) was 80% of her base salary (as compared to her target bonus for 2020 of 75% of her base salary, which has not changed since she commenced employment with the Company in 2014.salary). The Compensation Committee believes this increase in her bonus target iswas appropriate based on her level of experience, and the Compensation Committee’s review of bonus targets for other peer group CEOs, (also based on proxy data available through Equilar).and the Compensation Committee’s belief that significant portions of total annual cash compensation should be tied to achievement of specified goals. The bonus she received


earned for 20192021 was $712,296$807,619 which represents 120%121.6% of the net funded amount under the company’s Employee Bonus Plan (“EBP”). This amounther target bonus opportunity. Dr. Torley’s annual bonus was determined solely based on the Committee’s assessmentperformance of the Company and not any individual performance metrics. The 121.6% payout for 2021 reflected Dr Torley’s direct contributions to the Company’s strong performance throughout 2019 as well as Dr. Torley’s significant contributions during the year. Specifically, Dr. Torley:
Led the Company to be fully prepared for rapid BLA and MAA submissions and US and EU launches upon regulatory approval, assuming positive data from HALO-301,
Led detailed scenariosfinancial and operational planning to be prepared for immediate execution upon both positive and negative outcomes of HALO-301 study,
Ledperformance against the effective and clear external and internal communication ofgoals established by the negative HALO-301 clinical study results and subsequent prompt decisive actions related to the new corporate strategy and structure, and
Led the development, with input from the Board, bankers and advisors, of the company’s capital return plan which included successful execution of a $460 million convertible debt offering, of which $200 million was used to repurchase $200 million in shares prior to the end of the first quarter of 2020.

In addition, Dr. Torley continued to build organizational capabilities that position the Company for future growth and success.Compensation Committee under our Executive Bonus Plan as described below.
Dr. Torley also received a Long-Term Incentive (“LTI”)an LTI award during 20192021 that had a grant date fair value approximately $5,800,000, comprising the most significant element of $4,368,250 that was delivered 50% in stock options and 50% in time-vesting restricted stock units.her 2021 compensation opportunity. This award was granted as a result ofbased on the Compensation Committee’s assessment of her contribution to Halozyme’s performance during 2018 and2020, its review of LTI compensation paid to other peer group CEOs (based on proxy data available through Equilar).and the desire to link a significant portion of her realizable compensation to long-term performance. The Compensation Committee utilized thisapproved a mix of 25% PSUs (at target), 30% stock options and 45% RSUs for Dr. Torley and each of the other NEOs to focus management on the achievement ofemphasize Halozyme’s long-term goals designedstock price performance and to drive shareholder value creation, replicating a stockholder’s ownership position at any point in time. Stock option grantspromote retention. The stock options vest 25% on the one-year anniversary of the date of grant andwith the remaining options vest75% vesting monthly over the following three years, while restricted stock unit grantsRSUs vest in 25% annuallyannual installments over a four-year period beginning one year following the grant date. The Committee believes this vesting schedule aligns with practicesdate, subject to continued
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employment. PSUs granted to the NEOs in 2021 vest based on our relative total shareholder return measured against the component companies of other biopharmaceutical companies while providingthe NASDAQ Biotechnology Index over a reasonable level of retention incentive.three-year performance period.
Halozyme’s Executive Compensation Program
The principal elements of our executive compensation program are base salary, an annual cash incentive and an annual LTI award opportunity (consistingopportunity. The LTI awards for 2021 consisted of stock options, RSUs and restricted stock units).
PSUs.
What We DoWhat We Do Not Do
What We DoWhat We Do Not Do
ü


Pay annual bonus based on the achievement of Company financial and strategic goals, and in the case of NEOs other than the CEO, individual performance, and contribution in achieving those goals

×No guaranteed annual bonus payouts
ü

Grant PSUs as significant portion of annual LTI awards for all executive officers×No buyback of stock awards or repricing of stock options without shareholder approval
ü

Cap the annual bonus plan payout×No buyback or repricing of stock optionsexecutive single-trigger change in control benefits
üProhibit executive officer hedging and pledging of Company stock×No executive single-trigger change in control benefitsmaterial perquisites
ü

Maintain an executive officer recoupment (“claw back”) policy×
No on-goingsupplemental executive perquisites other than selective relocation reimbursements
benefits
ü

MonitorMaintain and monitor robust stock ownership and retention guidelines for all executive officers×No supplemental executive benefitsexcise tax gross-ups
ü

Conduct an annual comprehensive compensation program risk assessment×
No excise tax gross-ups within ongoing executive compensation arrangements




Detailed Discussion and Analysis
This CD&A describes the material elements of 2021 compensation paid to the NEOs during 2019.for our NEOs. Following this discussion is a series of tables containing specific data about the compensation earned by or granted to the following NEOs in 2019:
2021:
NamePrincipal Position
Helen I. TorleyPresident and Chief Executive Officer
Laurie
Elaine D. Stelzer Sun (1)
former Senior Vice President, Chief Financial Officer (“CFO”)
Harry J. Leonhardt (1)former
Masaru Matsuda (2)
Senior Vice President, General Counsel, Chief Compliance Officer and Corporate Secretary
Alison Armour (1)Michael J. LaBarreformer Senior Vice President, Head of Research & Development
Benjamin J. Hickey (1)former Senior Vice President, Chief CommercialTechnical Officer (“CCO”)
________________
(1) Ms. StelzerSun separated employment from Halozyme on March 6, 2020 to pursue another employment opportunity. Messrs. Leonhardt and Hickey and Dr. ArmourFebruary 2, 2022.
(2) Mr. Matsuda separated employment from Halozyme on January 3, 2020 as part of the restructuring implemented following the results of our HALO-301 Study.December 31, 2021.

The Compensation Committee makes all decisions relative to the total direct compensation (base salary, annual cash incentive, and LTI awards) of all executive officers (including the CEO). Except as otherwise noted in this CD&A, the Compensation Committee’s executive compensation determinations are subjective and the result of the Compensation Committee’s business judgment. Additional details regarding the role and responsibilities of the Compensation Committee are provided below.
In May 2019, Dr. Armour joined Halozyme as Senior Vice President & Head of Research & Development and was provided with a total compensation offer and certain other benefits related to her relocation to the San Diego area, that were competitive with external market practices for executives with similar experience in comparable roles. Amounts received by Dr. Armour in 2019 are described in further detail within the Summary Compensation Table.
Elements of Executive Compensation for 20192021
The material elements of 20192021 compensation for our NEOs consisted of:
base salary;
annual cash incentive; and
LTI compensation.awards.
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In addition, our NEOs are eligible to receive severance payments and benefits in connection with a qualifying termination of employment under our executive Change-in-Control Agreements and our severance policy for covered terminations unrelated to a change in control, each as described in more detail below. We also provide our NEOs with the same package of employee benefits that are provided to substantially all our full-time employees, including Company matching contributions to a 401(k) plan, health insurance, group term life insurance, and disability income insurance. From time to time, we may also provide recognition awards, gifts of nominal value or a relocation allowanceassistance in connection with the recruitment of an officer or employee (including an executive officer) with needed skills and experience. No othermaterial perquisites or supplemental executive benefits arewere provided to our NEOs.


NEOs in 2021.
As shown inbelow, the illustration below, a significant portionmajority of our NEOs’ “target”target total direct compensation isfor 2021 (base salary, target annual cash incentive, and LTI awards) was variable, andwith the single largest component (LTI awards, taken into account at their fair value on the grant date) based on Halozyme’s stock price performance.
ceopaya01.jpgceocharta.jpg
otherneospaya01.jpgotherneoa.jpg

Base Salary
The Compensation Committee determines base salaries for NEOs each year based upon the following factors (with no specific weight applied to each factor):
the scope and complexity of the NEO’s responsibilities,
25


a review of external market practices and survey results (a more detailed description of the methodology used to assess external market practices is provided below),
the NEO’s experience, prior to joining Halozyme, and
the CEO’s evaluation of the NEO’s performance and contribution to the short and long-term success of Halozyme (in the case of the CEO, the evaluation is done in executive session by the Compensation Committee in collaboration with input from the fullother independent members of the Board of Directors).
Base salary levels are reviewed annually. For 2019,2021, base salary was increased by 5.0%4.9% for the CEO and an average of 4.7%4.0% for our other NEOs as reflected in the table below. These adjustments reflect a meritThe rationale for Dr. Torley’s base salary increase consistent with both market practicesis discussed above. The base salary increases for our other NEOs were approved by the Compensation Committee after taking into account the base salaries paid to peer group executives holding similar positions and recognition of the contributions made during 2018.other factors described above.

Executive Officer2020 Base Salary2021 Base Salary% Increase
Helen I. Torley$791,440$830,2214.9%
Elaine D. Sun$475,000$494,0004.0%
Masaru Matsuda$440,000$457,6004.0%
Michael J. LaBarre$475,000$494,0004.0%

Executive Officer 2018 Base Salary2019 Base Salary% Increase
Helen I. Torley $725,000$761,0005.0%
Laurie D. Stelzer $470,000$495,0005.3%
Harry J. Leonhardt $442,000$464,0005.0%
Alison Armour (1) N/A$495,000N/A
Benjamin J. Hickey $465,000$483,0003.9%
(1)    Dr. Armour’s employment with Halozyme commenced on May 6, 2019.
Annual Cash Incentive
NEOs participate each year in the EBP.Employee Bonus Plan (“EBP”). The actual cash incentive paid to each NEO with respect to 20192021 was determined by the performance of Halozyme as measured by the level of achievement of ninefour metrics, inof which two overarching categoriesare tied to financial performance and have a combined 60% weighting and two are tied to operational performance and have a combined 40% weighting (“Corporate Performance”). Additionally,As CEO, Dr. Torley is responsible for overall corporate performance, and accordingly, her EBP incentive opportunity is based entirely on the attainment of objective, pre-established corporate performance goals without applying an individual performance adjustment. For the other NEOs, the Committee may modify final payouts based on individual performance during the year relative to the level of achievement of personal goals (“Individual Performance Factor”) but, and the total payout cannot exceed two times the target cash incentive opportunity for the NEO. Additionally, NEOsNEO must achieve at least 60% of his/her individual performance objectives in order to be eligible for a cash incentive payment. CashIn all events, an NEO’s total payout cannot exceed two times the target cash incentive payments are proratedopportunity for new hires based on the number of days employed at Halozyme in 2019.NEO.
Corporate Performance. Corporate goals were established by the Compensation Committee as a way(with input from the full Board of Directors) to track and measuretie the achievementcompensation of key objectives during the year. The two overarching categories and weighting by which Corporate Performance was determined (and the EBP was funded) are summarized in the diagram below:
a2019bonusplana01.jpg

Within each of the categories, the Compensation Committee approved specific metrics and goals for Halozymeour NEOs to achieve. As described further below, these corporate goals, when taken together, are intended to measure the Company’s progress towardachievement of annual operating objectives andthat were viewed as long-term drivers of sustainable value creation. The incentive zone ranges between 50%0% and 200% for each of the tenfour metrics. The Board of Directors approved the threshold (50%), target (100%), and maximum (200%) funding goals/level of performance for each metric at the beginning of the year.
The 20192021 bonus plan focused on achievement of key events that resulted in i)(i) ENHANZE growth and value-creation, ii) PEGPH20 time to data-readout(ii) budgeted operating profit and resultant strategy clarity and, iii) launch readiness, assuming positive data. The bonus plan was weighted 55% on ENHANZE-related metrics and 45% on metrics related to PEGPH20.
(iii) certain other operational goals as identified in the table below. The Compensation Committee is responsible for certifying actual performance relative to these goals following completion of the fiscal year. As a result,After reviewing the Company’s performance results in 2021, the Compensation Committee determined 20192021 EBP funding was achieved at 106.5%121.6% of the target bonus opportunity for the NEOs with ENHANZE-related goals contributing 61.5% and PEGPH20-related goals contributing 45% (see table below).


Corporate GoalWeightTargetActual ResultEBP Funding
Total revenue from ENHANZE50%$421M$443.3M68.7%
Total budgeted operating profit10%$261M$275.9M12.9%
Grow ENHANZE potential by supporting partner attainment of “x” new study starts (phase 1, 2 or 3)25%101025.0%
Number of new co-formulation patent submissions by partner15%3315%
TOTAL121.6%
26

Corporate GoalWeightTargetEBP Funding
Revenue
Total revenue from ENHANZE25%$208M24%
Support from BLA Submission Readiness

   
Achieve HALO-301 database lock within “x” weeks of target OS events15%825.0%
HALO-301 CSR shell completed by time of database lock and within 9 weeks of target event achievement (no upside beyond 100%)5% 5%
Complete all defined Ventana companion diagnostic regulatory submission readiness milestones by database lock and within 9 weeks of target event achievement (no upside beyond 100%)

5% 5%
Advance demonstration of pan tumor potential:

   
achieve enrollment goal and go/no go decision by stated date in cholangiocarcinoma and gall bladder trial (no upside beyond 100%).

10%
75 patients & go/no go on June 30

—%
Be fully ready for execution of US Early Access Program upon positive data (no upside beyond 100%)

10%by October 110.0%
Grow ENHANZE potential by supporting partner attainment of “x” new study starts (phase 1, 2 or 3)

15%67.5%
Support Janssen on plan BLA and MAA filings by providing all required documentation by:

15%(1)30.0%
TOTAL106.5%

(1)We consider this goal target and actual performance relative to the goal as proprietary and confidential to our partner and to Halozyme. The target of this goal was set at a challenging level such that attainment of the target was not assured at the time it was set and achievement would require a high level of execution on the part of executive management.
Individual Performance Factor. The Compensation Committee believes the actual payout to each NEO (other than for Dr. Torley whose payout, as noted above, is based entirely on the attainment of objective, pre-established corporate performance goals) should also reflect the executive’s:
performance relative to individual goals and objectives established for the year,
contribution toward achieving the Corporate Performance results, and
demonstration of living Halozyme’s Leadership Attributes and Corporate Values during the year.

Weighing Dr. LaBarre’s accomplishments and other factors, the Compensation Committee awarded him 121.6% of his target bonus opportunity. The Compensation Committee noted that:
Ms. Stelzer,Dr LaBarre’s contributions to the strong 2021 performance included playing a key role in the new ENHANZE collaboration agreement with ViiV, providing advice and recommendations to multiple partners contributing to the 10 study starts in 2021 and contributions to multiple regulatory submissions advancing our manufacturing and partner programs.

As a result of his separation from employment in December 2021 and the resulting separation agreement, Mr. Leonhardt, Dr. Armour and Mr. Hickey eachMatsuda received the net funded amountan annual bonus for their 20192021 equal to his target bonus payout. Each executed on the operatingamount. Since our bonus plan and positioned the Companyrequires participants to be fully readyemployed by us at the time of payment, Ms. Sun was not paid an annual bonus for success had the outcome2021 as a result of the HALO-301 clinical trial been successful. Additionally, each had prepared detailed contingency plans in the event of negative data and following the negative HALO-301 study results, each executive quickly implemented restructuring plans and refocused the Company on the ENHANZE platform.



her separation from employment.
The table below illustrates the 20192021 cash incentive calculation for each NEO based on the following formula (also reflected in the “Non-Equity Incentive Plan Compensation” column of the Summary Compensation Table).
slide1b05a.jpg
Named Executive Officer 
Annualized Base Salary
($)
 
Target
%
 
Annualized
Target Amount
($)
 Corporate & Individual Performance Factor 
Final Payout
($)
Helen I. Torley 761,000 75% 570,750 124.8% 712,296
Laurie D. Stelzer 495,000 45% 222,750 104% 231,660
Harry J. Leonhardt 464,000 45% 208,800 104% 217,152
Alison Armour (1) 495,000 45% 222,750 104% 152,324
Benjamin J. Hickey 483,000 45% 217,350 104% 226,044
Named Executive OfficerAnnualized Base Salary
($)
Target
%
Annualized
Target Amount
($)
Corporate & Individual Performance FactorFinal Payout
($)
Helen I. Torley (1)
830,22180%664,177121.6%807,619 
Elaine D. Sun (2)
494,00045%222,300— 
Masaru Matsuda (3)
457,60045%205,920100%205,920 
Michael J. LaBarre494,00045%222,300121.6%270,217 
________________
(1)Dr. Armour’s employment with Halozyme commenced on May 6, 2019. Her final EBP payout amount was pro-rated for the number of days she was employed by Halozyme during 2019.

(1)As noted above, Dr. Torley’s payout is based entirely on the attainment of objective, pre-established corporate performance goals without applying an individual performance factor.
(2)As noted above, Ms. Sun did not earn an annual bonus for 2021 as a result of her separation from employment.
(3)Mr. Matsuda received the amount of his target annual bonus pursuant to his separation agreement with the Company described below.
LTI Compensation
All grants of LTI compensation are made under theour stockholder-approved Halozyme Therapeutics, Inc. 2011 Stock Plan.equity incentive plan. The Compensation Committee utilized two LTI deliverythree vehicles to grantdeliver LTI awards to NEOs during 2019:2021:
Stock Options are strongly aligned with stockholder interests because they deliver financial value to the NEO only if the value of our stock at the time of exercise exceeds the stock price on the day of grant. As a result, the Compensation Committee believes stock options encourage executives to focus on the decisions and behaviors required to support long-term sustainable increases in our stock price.
Time-vesting Restricted Stock Units (“RSUs”)RSUs replicate a stockholder’s ownership position at any point in time. Restricted stock also providesprovide a counterbalance to the more uncertain value associated with stock options.options and PSUs while still maintaining alignment with the interests of our long-term stockholders, as the value of RSUs fluctuates (up or down) with changes in our stock price. As a result, the Compensation Committee believes restricted stock encouragestime-vesting RSUs encourage executives to make decisions consistent with the long-term interests of our stockholders.stockholders and help support retention.
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Stock options and time-vesting RSUs granted to our NEOs in 2021 generally vest over a four-year period subject to continued employment.
2019PSUs, which we added to our NEO executive compensation program for 2021, help link our equity incentive program to achievement of specific performance goals established by the Compensation Committee. The Compensation Committee believes that the grant of PSUs furthers our executive compensation philosophy to tie achievement of company performance with executive compensation, aligns the interests of executive officers with our stockholders and encourages long-term performance.
The PSUs granted to the NEOs in 2021 were eligible to be earned with respect to one-third of the target PSUs for one-, two-, and three-year performance periods based on our relative TSR measured against the component companies of the NASDAQ Biotechnology Index. Earned shares vest 100% at the end of the three-year period following certification of performance results and assuming continued employment (subject to earlier vesting and payment on a pro-rated basis on an involuntary termination). For these purposes, TSR for us and the component companies is based on a 20-trading day average trading price beginning on the PSU grant date and a 20-trading day trading price ending on the last day of the applicable performance period. Dividend equivalents, if any, will be accrued as additional stock units and delivered with earned shares at vesting. The potential vesting percentages for the 2021 PSUs are as follows (with the percentage determined by linear interpolation for performance between the 25th and 75th percentiles):
Maximum
75th Percentile or Higher
150%
Target
50th Percentile
100%
Threshold
25th Percentile
50%
Below Threshold
< 25th Percentile
0%

2021 Annual LTI Awards
For 2019,2021, the Compensation Committee awarded annual LTI compensation for the NEOs based on the fair value theythe committee determined appropriate considering factors (with no specific weight appliedtheir assessment of annual equity award grants to each factor) such as the competitive market,peer group executives holding similar positions, and taking into account their assessment of the executive’s experience, the executive’s expected contribution to the long-term success of the Company, and the executive’s skill-set relative to industry peers at biopharmaceutical companies. After considering these factors,companies (with no specific weight applied to each factor). The Compensation Committee also determined that the award value for each NEO would be allocated 25% PSUs (at target), 30% stock options and 45% RSUs. Accordingly, the Compensation Committee awarded the following LTI compensation fair values to our NEOs in 2019:2021:
NameOption Awards
($)
RSUs
($)
PSUs
($)
Total
($)
Helen I. Torley1,740,001 2,610,021 1,450,060 5,800,082
Elaine D. Sun495,009 742,516 412,545 1,650,070
Masaru Matsuda450,010 675,033 375,007 1,500,050
Michael J. LaBarre450,010 675,033 375,007 1,500,050
Name 
Option Awards
($)
 
RSUs
($)
 
Total
($)
Helen I. Torley 2,184,128
 2,184,130
 4,368,258
Laurie D. Stelzer 750,005
 750,016
 1,500,021
Harry J. Leonhardt 625,007
 625,008
 1,250,015
Alison Armour (1) 1,000,002
 1,000,006
 2,000,008
Benjamin J. Hickey 625,007
 625,008
 1,250,015
(1)Dr. Armour’s 2019 LTI award was granted following her commencement of employment with Halozyme as an inducement to join the company. With the negative data outcome, none of her awards vested prior to the conclusion of her employment.

Executive Total Rewards Philosophy
The Compensation Committee periodically reviews its total rewards philosophy for executive officers to confirm it continuesour programs continue to meet the objectives of:
supporting the short- and long-term business strategy,
anchoring to market-based principles and tailored to Halozyme’s culture, and
aligning the interests of the executive officers with the long-term interests of Halozyme stockholders.
Each of the three primary compensation elements has a specific purpose and competitive positioning within the peer group as described below:
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Compensation ElementPurposeTarget Market Positioning
Base Salary• Provides a fixed amount of cash compensation based on individual performance, job scope, experience and competitive market for talent
• 50th percentile with adjustments depending upon experience, responsibilities and expected contribution
Annual Cash Incentive• Motivates and rewards fiscal year contribution to company performance against goals and objectives
• 50th percentile target bonus opportunity with adjustments based on overall corporate and individual performance
Long-term Incentives (LTI)
AlignsAlign compensation with the creation of sustainable stockholder value (in the case of stock options) and changes in stock price (in the case of RSUs and PSUs)
• Increases executive stock ownership and align with stockholder interests.
• Serves as a key retention device
• 50th percentile target LTI opportunity with adjustments based on overall corporate and individual performance and expected contribution


Competitive Peer Group
The Compensation Committee annually selects a group of peer companies for competitive analysisagainst which Halozyme benchmarks the competitiveness of executive compensation.pay levels and program design (referred to in this CD&A as our “peer group” or “peer companies”). The peer group companies are identified based upon the Compensation Committee’s assessment of each company’s similarity with Halozyme with respect to science/business model, revenue, and market capitalization, and employee headcount.. The peer group is reviewed annually and adjusted as needed to ensure thatby the peer companies continue to share similarities with Halozyme.Compensation Committee. For 20192021 compensation decisions, the Compensation Committee utilized proxy peer group data from the following companies:

20192021 Peer Group
Array BiopharmaAcadia Pharmaceuticals
Acceleron Pharmaceuticals
Agios Pharmaceuticals
Alnylam Pharmaceuticals
Eagle Pharmaceuticals
FibroGen Inc.
Exelixis, Inc.
Five PrimeHeron Therapeutics
Genomic Health
Innoviva
Intercept Pharmaceuticals
Ironwood Pharmaceuticals
Lexicon Pharmaceuticals
Ligand Pharmaceuticals
Momenta Pharmaceuticals
Nektar Therapeutics
Pacira
Neurocrine Biosciences
Sarepta Therapeutics
Theravance Biopharma
Travere Therapeutics
Ultragenyx Pharmaceuticals
Seattle Genetics
Spectrum Pharmaceuticals
Vanda Pharmaceuticals

Changes
The following changes to the peer group were made (versus 2018)for 2021: Acadia Pharmaceuticals, Acceleron Pharmaceuticals, Agios Pharmaceuticals, Alnylam Pharmaceuticals, Heron Therapeutics, Intercept Pharmaceuticals, Neurocrine Biosciences, Sarepta Therapeutics, Theravance Biopharma, Travere Therapeutics, and Ultragenyx Pharmaceuticals were added to create a larger group with the Company at or near the median for both market capitalization and revenue. Innoviva Inc., Lexicon Pharmaceuticals, and PDL BioPharma were removed from the group because they were significantly smaller than the Company in market capitalization.
Independent Compensation Consultant
The Compensation Committee retains F.W. Cook & Co. (“FW Cook”) as its independent compensation consultant to provide advice and counsel on matters related to our executive compensation program, including providing recommendations regarding the composition and selection of Halozyme’s peer group companies to be used with respect to 2021 and 2022 executive compensation decisions and assisting and advising with respect to the design and implementation of the annual LTI awards. FW Cook reports directly to the Compensation Committee. The Compensation Committee assessed the independence of FW Cook pursuant to applicable rules and regulations of the SEC and NASDAQ and concluded that (i) eliminated recently acquired companiesthe engagement of FW Cook did not raise any conflicts of interest during fiscal 2021 and companiescurrently does not raise any conflicts of interest.
2021 Say-On-Pay Vote
At our 2021 annual meeting of stockholders, our stockholders approved, on a non-binding, advisory basis, the compensation paid to our NEOs described in our 2021 proxy statement. Approximately 98.2% of the votes cast on the matter
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were voted in favor of this “say-on-pay” proposal. The Compensation Committee considered the voting results and high level of stockholder support when establishing our executive compensation programs for fiscal 2022.
Compensation Risk Assessment
Our Compensation Committee, with assistance from its independent compensation consultant and with input from members of management, annually reviews our compensation programs, policies and practices to determine whether they encourage risk-taking that could have a material adverse effect on the Company. As part of this review, the Company evaluates the primary components of its compensations plans to identify whether those components properly balance compensation opportunities and risk. Our Compensation Committee considers various factors, including the following:
The Company’s pay philosophy provides an effective balance in cash and equity award mix, short- and long-term performance periods, financial and non-financial performance, formulas and discretion.
The Company’s compensation programs include an appropriate mix of short- and long-term goals and incentives.
The Compensation Committee has discretion to make positive and negative adjustments to payouts under the Company’s compensation plans.
Policies are no longer considered comparablein place to Halozyme’s business,manage or mitigate risk, such as stock ownership guidelines, vesting periods on equity awards, insider-trading prohibitions that also restrict hedging and (ii) added companiespledging, recoupment policy and provisions, and independent Compensation Committee oversight.
The Company’s design and oversight principles also apply to its broad-based employee compensation plans.
Based on this review, the Compensation Committee, based in part on the input from its compensation consultants, concluded that were more closely aligned with Halozyme’s business.the risks arising from the Company’s compensation policies and practices, for both our executive officers and our other employees, are not reasonably likely to have a material adverse effect on Halozyme.
Other Compensation Matters
Stock Ownership and Retention Guidelines
During 2016, the Board of Directors adopted increasedWe maintain stock ownership guidelines for our executive officers which stipulate that the CEO is expected to own shares of Halozyme common stock with value equal to no less than foursix times the CEO’s current base salary and that all other executive officers are expected to own shares of Halozyme common stock with value equal to no less than two times the officer’s current base salary. In additionWe increased the CEOs ownership multiple in February 2021 (from four times base salary to increasingsix times base salary) to further enhance the stock ownership guidelines for executive officers, in 2016 the Boardlink between her interests and those of Directors also adopted stock ownership guidelines for certainour long-term stockholders. Certain other officersexecutives designated by the Compensation Committee which stipulate that they are expected to own shares of Halozyme common stock with value no less than one times the officer’s current base salary. Each executive officer is expected to comply with the guidelines within five years of appointment as an executive officer.officer, and has three years to comply with any incremental ownership required as a result of a promotion or other increase in applicable ownership multiple. Share ownership that counts for purposes of satisfying the applicable guideline level of ownership includes fully-owned shares (including shares held in trust and by immediate family members), vested but deferred shares, shares held in retirement accounts, and unvested stock units that are subject to time-based vesting only. Stock units subject to unsatisfied performance-based vesting conditions and unexercised stock options are not counted when evaluating compliance. Each executive officer is required to: (i) hold at least 50% of all net shares (after shares withheld or sold to pay tax obligations) of restricted stockRSUs and PSUs that vests;vest; and (ii) hold at least 50% of the underlying net gain (i.e., not including shares sold to pay the exercise price or to satisfy tax obligations) in shares of the Company’s common stock as a result of stock option exercises, until the executive officer comes into compliance with the stock ownership guidelines. The Compensation Committee annually reviews progress executive officers are making toward achieving compliance with these guidelines and has determined that all executive officerof our NEOs have achieved their specific ownership levels.
Tax Deductibility of Executive Compensation
Section 162(m) of the Internal Revenue Code generally disallows a tax deduction to public companies for any publicly held corporation for individual compensation exceeding $1.0in excess of $1 million in any taxable year for its “covered employees.” Priorpaid to the Tax Cuts and Jobs Act of 2017, covered employees generally consisted of a corporation’scompany’s chief executive officer and the three next most-highly compensatedcertain current and former executive officers (other than its chief financial officer)officers. As a result, we expect that compensation paid per year to our NEOs and compensation that qualified as “performance-based compensation” for purposes of Section 162(m) of the Code was exempt from this $1.0 million deduction limitation. As part of the Tax Cuts and Jobs Act of 2017, the ability to rely on this exemption was, with certain limited exceptions, eliminated; in addition, the determination of the covered employees was generally expanded. In light of the repeal of the performance-based compensation exception to Section 162(m) of the Code, the Company may not be able to take a deduction for any compensationformer executive officers in excess of $1.0$1 million thatgenerally will not be deductible, subject to limited exceptions. The Compensation Committee generally seeks to preserve tax deductions for executive compensation where available but may make compensation decisions based on other factors when it believes doing so is paid to a covered employee.


in the best interest of the Company and its stockholders.
Change in Control Agreements
We have entered into Change-in-ControlChange in Control Agreements with our executive officers. The Change-in-Control AgreementsWe believe that the occurrence or potential occurrence of a change in control transaction creates uncertainty regarding the continued employment of our executive officers. This uncertainty results from the fact that many change in control transactions are common in our industry and often
30


result in significant organizational changes, particularly at the senior executive level. To encourage executives to remain employed with the Company during an important time when their prospects for continued employment following the transaction are often uncertain, we provide for cash payments, continued healthcare coverage and accelerated vesting of equity awards for any suchour executive officer who is terminated for a reason other than cause within 12 months following a change-in-control transaction. The cash payments, to be made in a lump sum payment, will equal: (i) a multiple of the executive officer’s then-current base salary (twice the base salary of the Company’s CEO and one-and-a-half times the base salary of the other executive officers); and (ii) the amount of target annual bonus opportunity (based on the target percentage of annual base salary) in respect of the year the termination of employment occurs. The Company will also make a cash lump sum payment intended to provide the executive officer sufficient amounts to pay expected healthcare premiumsofficers with additional severance protections under the Company’s group health plans for 18 months post termination of employment (24 monthsChange in Control Agreements. We also provide these severance protections to help ensure that executives can objectively evaluate change in control transactions that may be in the casebest interests of stockholders despite the CEO). The Change-in-Control Agreements also provide that the amount of severance benefits could potentially be subject to reduction to the extent that the total payments (as defined in the Change-in-Control Agreements) constitute an “excess parachute payment” under Section 280G of the Internal Revenue Code of 1986, as amended (“Code”), or become subject to the excise tax imposed under Section 4999 of the Code.
Employment Agreements
The Company does notpotential negative consequences such transactions may have written employment agreements with executive officers.on them personally.
Non-Change in Control Severance Policy
The Compensation Committee has approved a companywideCompany-wide severance policy, outside of a change in control context, that is also applicable to our executive officers whoofficers. We believe that such severance protections are terminated byonly appropriate in the Companyevent an executive is involuntarily terminated without cause and that these severance benefits are appropriate in the following respect: the cashlight of severance for the executive officer will be equalprotections available to (i) the executive officer’s then-current annual base salary (1.5X for the CEO), plus (ii) a pro-rata amount equalexecutives at our peer group companies, and are an important component of each executive’s overall compensation as they help us to the executive officer’s target bonus opportunity for the year during which the separation of employment occurs based on the number of days employed during the year. Cash payments under the severance policy will normally be made in a lump sum payment, subjectattract and retain our key executives who could have other job alternatives that may appear to standard taxes and withholdings, and will be conditioned upon the receipt of a release of claims from the executive officer. In addition to cash severance payments, the Company will also allow vested stock options (at the time of separation)them to be exercisable for one year from the date of separation (or when the option expires, if earlier) and pay certain health coverage costs during the term of the applicable severance period.more attractive absent these protections. Despite the establishment of the severance policy, however, the Board of Directors or Compensation Committee retains the right to amend, alter or terminate the severance policy at any time.
As an inducementSeparation Agreement with Mr. Matsuda
Mr. Matsuda separated employment from the Company, effective December 31, 2021. In connection with his separation, the Company negotiated and entered into a separation agreement with Mr. Matsuda that provided for him to relocatereceive cash severance in a lump sum equal to the United States, Mr. Hickey was offered a special severance arrangement that would replace the above executive officer severance policy in the event thatone year of his base salary ($457,600) and his target annual bonus for 2021 ($205,920). In addition, he is involuntarily terminated not for Cause or for Good Reason (both as defined within the Change in Control Agreement) during the first 18 months of employment with Halozyme. Under this arrangement he would receive (i)received a cash severance lump sum payment equalfor his COBRA premiums for 12 months (plus an additional amount to 1.5Xcover his then current annualized base salary, (ii) 18 months’tax liabilities for this payment) and will have up to 12 months following his separation date to exercise his vested Company stock options. Benefits were conditioned on a general release of COBRA benefits continuation paid forclaims by Halozyme,Mr. Matsuda, and (iii) any portion ofhe remains subject to certain restrictive covenants under his cash sign-on bonus that remains unpaid atconfidentiality agreement with the time of termination.Company.
Incentive Compensation Recoupment (“Clawback Policy”)
The Compensation Committee has approved an incentive compensation recoupment policy which provides for the recovery of compensation received by NEOs in connection with a material restatement in Halozyme’s financial statement disclosure. The Board of Directors willmay seek reimbursement of annual cash incentive compensation and all equity compensation awards where the payout or vesting exceeds the amounts that would have been received had the financial results been properly reported.
Hedging and Pledging Restrictions
The Company’s Insider Trading Policy prohibits the pledging the Company’sof Company securities as collateral and entering into transactiontransactions to hedge the value of the Company’sCompany securities owned by executives subject to the policy. Accordingly, underUnder the policy all directors and employees (including officers), or their designees, are prohibited from purchasing financial instruments (including prepaid variable forward contracts, equity swaps, collars and exchange funds) or otherwise engage in transactions, that hedge or offset, or are designed to hedge or offset, any decrease in the market value of Halozyme’s equity securities that are either (i) granted to the employee or director by Halozyme as part of the compensation of the employee or director or (ii) held, directly or indirectly, by the employee or director.


Compensation Committee Report
We, the Compensation Committee of the Board of Directors of Halozyme Therapeutics, Inc., have reviewed and discussed the Compensation Discussion and Analysis contained in this Proxy Statement with management. Based on such review and discussion, we have recommended to the Board of Directors that the Compensation Discussion and Analysis be included in this Proxy Statement.
THE COMPENSATION COMMITTEE
Connie L. Matsui
Bernadette Connaughton (Chair)
Jean-Pierre Bizzari, M.D.
Bernadette Connaughton
Jeffrey W. Henderson



31


Summary Compensation Table
The following table sets forth information concerning the compensation earned during the fiscal years ended December 31, 2019, 20182021, 2020 and 20172019 by each individual who acted as our principal executive officer, our principal financial officer, and our other most highly compensated executive officers during the fiscal year ended December 31, 20192021.
2021 SUMMARY COMPENSATION TABLE
Name and Principal PositionYearSalary
($)
Bonus
($)
Stock
Awards
($)(1)(3)
Option Awards
($)(2)(3)
Non-Equity
Incentive Plan
Compensation
($)(4)
All Other
Compensation
($)(5)
Total
($)
Helen I. Torley2021830,2214,060,0811,740,001807,61915,3727,453,294
President and
Chief Executive Officer
2020791,4402,500,0182,500,001712,27015,1476,518,876
2019761,0002,184,1302,184,128712,29615,5725,857,126
Elaine D. Sun (6)
2021494,0001,155,062495,00914,2712,158,342
Senior Vice President
Chief Financial Officer
2020395,833150,0001,500,2691,000,008180,352133,3993,359,861
Masaru Matsuda (7)
2021457,600(9)1,050,040450,010205,920594,4592,758,029
Senior Vice President, General Counsel, Chief Compliance Officer and Corporate Secretary2020440,00050,000500,019500,008203,94013,9011,707,868
Michael J. LaBarre (8)
2021494,0001,050,040450,010270,21715,3332,279,600
Senior Vice President, Chief Technical Officer2020475,000650,009650,007220,16315,0182,010,197
________________
(1)This column represents the grant date fair value of stock awards granted to the NEOs in fiscal years 2021, 2020 and 2019, in accordance with the Financial Accounting Standards Board’s (“FASB”) Accounting Standards Codification (“ASC”) Topic 718. Pursuant to SEC rules, the amounts shown exclude the impact of estimated forfeiture related to service-based vesting conditions. For additional information on the valuation assumptions used by us in calculating these amounts refer to Note 7 of the Notes to Consolidated Financial Statements, filed as part of our Annual Report on Form 10-K for the fiscal year ended December 31, 2021 filed with the SEC on February 22, 2022. Stock awards granted to executive officers consist of RSUs and PSUs. A portion of the amounts reported in this column for each NEO for fiscal 2021 and in the case of Ms. Sun, fiscal 2020 reflect the grant-date fair value of PSUs granted to the executives during that fiscal year. In accordance with applicable SEC rules, these amounts were determined based on the probable outcome (determined as of the date of grant of the awards) of the performance-based conditions applicable to the awards.For these purposes, the grant date fair value for the PSU awards granted to each of the NEOs in 2021 and to Ms. Sun in 2020 was determined based on a Monte Carlo simulation pricing model (which probability weights multiple potential outcomes) as of such grant date. The significant assumptions used in the Monte Carlo simulation pricing model were: a stock price volatility rate of 40.96%; a risk-free interest rate of 0.20%; and a dividend yield of 0%. The following table presents the aggregate grant-date fair value of these performance-based awards granted in fiscal 2021 and 2020 included in the “Stock Awards” column for those years and the aggregate grant-date fair value of these awards assuming that the highest level of performance conditions was achieved.

Aggregate Grant Date Fair Value of Performance Awards (Fiscal 2021)Aggregate Grant Date Fair Value of Performance Awards (Fiscal 2020)
Name
Based on Probable Outcome as of the Grant Date
($)
Based on Maximum Performance
($)
Based on Probable Outcome as of the Grant Date
($)
Based on Maximum Performance
($)
Helen I. Torley1,450,0602,175,060
Elaine D. Sun412,545618,818500,264500,264
Masaru Matsuda375,007562,510
Michael J. LaBarre375,007562,510
32


(2)This column represents the grant date fair value of stock options granted to the NEOs in fiscal years 2021, 2020 and 2019, in accordance with FASB ASC Topic 718. Pursuant to SEC rules, the amounts shown exclude the impact of estimated forfeiture related to service-based vesting conditions. For additional information on the valuation assumptions used by us in calculating these amounts refer to Note 7 of the Notes to Consolidated Financial Statements, filed as part of our Annual Report on Form 10-K for the fiscal year ended December 31, 2021 filed with the SEC on February 22, 2022.
(3)The amounts reported in the Summary Compensation Table for stock awards and option awards may not represent the amounts that the NEOs will actually realize from the awards. Whether, and to what extent, an NEO realizes value will depend on stock price fluctuations and the NEO’s continued employment. To see the exact share amounts and the value of awards made to the NEOs in fiscal 2021, see the 2021 Grants of Plan-Based Awards table below. Additional information on all outstanding awards is reflected in the Outstanding Equity Awards at December 31, 2021 table.
(4)Performance-based bonuses are generally paid pursuant to our annual incentive plans and reported as Non-Equity Incentive Plan Compensation. The performance-based bonuses represent amounts earned during each respective fiscal year, regardless of whether part or all of such amounts were paid in a subsequent fiscal year. For Ms. Sun, her performance-based bonus for 2020 was pro-rated to account for her date of hire.
(5)The table below lists the amounts set forth in this column which consist of other compensation including (i) Company contributions to Halozyme Therapeutics, Inc. 401(k) plan, (ii) payout of accrued paid time off for Mr. Matsuda and (iii) other compensation amounts including Company payments for group term insurance premiums, and (iv) severance payments for Mr. Matsuda (including the cash lump sum severance payment of $457,600, $37,783 for 12 months of continued COBRA premiums, and $26,234 for tax liabilities with respect to the payment for continued COBRA premiums.
Name401(k) Plan Company Matching Contributions ($)Payout of Accrued Paid Time Off ($)Other Compensation ($)Termination Payments ($)Total ($)
Helen I. Torley$13,050$2,322$15,372
Elaine D. Sun$13,050$1,221$14,271
Masaru Matsuda$13,05058,670$1,122521,617$594,459
Michael J. LaBarre$13,050$2,283$15,333
(6)Ms. Sun joined Halozyme as Senior Vice President, Chief Financial Officer effective March 2, 2020. The amounts in the Bonus, Stock Awards and Option Awards columns for 2020 represent a one-time sign-on bonus, stock and option awards granted to her in connection with joining the Company.
(7)Mr. Matsuda separated employment from the Company on December 31, 2021. The terms of his separation agreement with the Company are described below under “Potential Payments Upon Termination or Change in Control”. Mr. Matsuda became an executive officer of the Company in 2020. The amount in the Bonus column for 2020 represents the final installment of his sign-on cash bonus paid in connection with the commencement of his employment.
(8)Dr. LaBarre became an executive officer of the Company in 2020.

33
2019 SUMMARY COMPENSATION TABLE
Name and Principal Position Year Salary
($)
 Bonus
($)
 Stock
Awards
($)(1)
 Option Awards
($)(2)
 Non-Equity
Incentive Plan
Compensation
($)(3)
 All Other
Compensation
($)(4)
 Total
($)
Helen I. Torley 2019 761,000
  2,184,130
 2,184,128
 712,296
 15,572

5,857,126
President and
Chief Executive Officer
 2018 725,000
  2,115,640

2,115,631
 831,665
 11,733

5,799,669
 2017 671,000
  1,900,011

1,900,003
 699,115
 10,422

5,180,551
                 
Laurie D. Stelzer 2019 495,000
 2,500(5)750,016
 750,005
 231,660
 16,939

2,246,120
Former Senior Vice President,
Chief Financial Officer
 2018 470,000
  575,018
 575,009
 323,489
 9,409

1,952,925
 2017 452,000
  550,006
 550,000
 282,563
 9,210

1,843,779
                 
Harry J. Leonhardt 2019 464,000
  625,008
 625,007
 217,152
 16,536

1,947,703
Former Senior Vice President, General Counsel 2018 442,000
  575,018
 575,009
 304,218
 11,355
 1,907,600
  2017 425,000
  550,006
 550,000
 242,582
 11,070
 1,778,658
                 
Alison Armour (6) 2019 324,375
 200,000(7)1,000,006
(7)1,000,002
(7)152,324
 1,990

2,678,697
Former Senior Vice President, Head of Research & Development 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
                 
Benjamin J. Hickey 2019 483,000
 121,000(8)625,008

625,007

226,044
 121,998
(9)2,202,057
Former Senior Vice President,
Chief Commercial Officer
 2018 145,313
 180,000(8)1,500,009
(8)1,500,004
(8)86,160
 91,485
(10)3,502,971
 
 
 




 
 

 


________________
(1)
This column represents the grant date fair value of stock awards granted to the NEOs in fiscal years 2019, 2018 and 2017, in accordance with the Financial Accounting Standards Board’s (“FASB”) Accounting Standards Codification (“ASC”) Topic 718. For additional information on the valuation assumptions used by us in calculating these amounts refer to Note 7 of the Notes to Consolidated Financial Statements, filed as part of our Annual Report on Form 10-K for the fiscal year ended December 31, 2019 filed with the SEC on February 24, 2020. Stock awards granted to executive officers consist of restricted stock units. The amounts shown are the grant date fair value in accordance with the authoritative guidance for stock-based compensation. The weighted average grant date fair value of stock awards granted in 2019, 2018 and 2017 was $16.37, $18.45, and $12.07 per share, respectively, based on the closing prices of Halozyme common stock on the grant dates.
(2)
This column represents the grant date fair value of stock options granted to the NEOs in fiscal years 2019, 2018 and 2017, in accordance with FASB ASC Topic 718. To see the exact share amounts and the value of awards made to the NEOs in fiscal 2019, see the 2019 Grants of Plan-Based Awards table below. Pursuant to SEC rules, the amounts shown exclude the impact of estimated forfeiture related to service-based vesting conditions. For additional information on the valuation assumptions used by us in calculating these amounts refer to Note 7 of the Notes to Consolidated Financial Statements, filed as part of our Annual Report on Form 10-K for the fiscal year ended December 31, 2019 filed with the SEC on February 24, 2020. The amounts reported in the Summary Compensation Table for these awards may not represent the amounts that the NEOs will actually realize from the awards. Whether, and to what extent, an NEO realizes value will depend on stock price fluctuations and the NEO’s continued employment. Additional information on all outstanding awards is reflected in the Outstanding Equity Awards at December 31, 2019 table.


(3)Performance-based bonuses are generally paid pursuant to our annual incentive plans and reported as Non-Equity Incentive Plan Compensation. The performance-based bonuses represent amounts earned during each respective fiscal year, regardless of whether part or all of such amounts were paid in a subsequent fiscal year.
(4)Except as noted in footnotes 9 and 10, the amounts set forth in this column consist of other compensation including (i) Company contributions to Halozyme Therapeutics, Inc. 401(k) plan (other than Dr. Armour), (ii) other compensation amounts (none of which exceeded $10,000) including (a) Company payments for group term insurance premiums, (b) for 2019 amounts, a Company-sponsored gift of nominal value for all employees (including a one-time only tax gross up) and (c) for Ms. Stelzer’s 2019 amount, a one-time only tax gross up on her recognition award.
(5)Represents a one-time recognition award.
(6)Dr. Armour joined Halozyme as Senior Vice President, Head of Research & Development effective May 6, 2019.
(7)Represents, in the respective columns, a one-time sign-on cash bonus, stock award and option award to Dr. Armour in connection with her recruitment as Senior Vice President, Head of Research & Development.
(8)Represents, in the respective columns, a sign-on cash bonus, stock award and option award to Mr. Hickey in connection with his recruitment as Chief Commercial Officer.
(9)Includes the reimbursement of approximately $109,000 in relocation expenses, which includes a tax gross-up of $56,000.
(10)Includes the reimbursement of approximately $90,000 in relocation expenses, which includes a tax gross-up of $45,000.


20192021 Grants of Plan-Based Awards
The following table sets forth certain summary information with respect to plan-based awards granted during the fiscal year ended December 31, 20192021 to our NEOs:
Estimated Future Payouts Under
Non-Equity Incentive Plan Awards(1)
Estimated Future Payouts Under
Equity Incentive Plan Awards (2)
All Other Stock Awards: Number of Shares or Units(#) (3)All Other Option Awards: Number of Securities Underlying Options(#) (4)Exercise or Base Price of Option Awards
($/Sh)
Grant Date Fair Value of Stock and Option Awards($) (5)
NameGrant DateThreshold
($)
Target
($)
Maximum
($)
Threshold
(#)
Target
(#)
Maximum
(#)
Helen I.
Torley
n/a— 664,177 1,328,354 
2/15/202152,368 2,610,021 
2/15/202111,434 22,868 34,302 1,450,060 
2/15/202190,134 49.84 1,740,001 
Elaine D. Sunn/a— 222,300 444,600 
2/15/202114,898 742,516 
2/15/20213,253 6,506 9,759 412,545 
2/15/202125,642 49.84 495,009 
— — 
Masaru Matsudan/a— 205,920 411,840 
2/15/202113,544 675,033 
2/15/20212,9575,914 8,871 375,007 
2/15/202123,311 49.84 450,010 
Michael J. LaBarren/a— 222,300 444,600 
2/15/202113,544 675,033 
2/15/20212,957 5,914 8,871 375,007 
2/15/202123,311 49.84 450,010 
________________
(1)For a description of the elements of the annual incentive plan applicable to our NEOs, refer to “Compensation Discussion and Analysis - Elements of Executive Compensation for 2021” in this proxy statement. The actual amount of cash paid to each NEO pursuant to the incentive plan established for 2021 is set forth in the Summary Compensation Table under the heading, “Non-Equity Incentive Plan Compensation.”
(2)The PSU awards to our NEOs were granted in February 2021 and vest based on our relative TSR measured against the component companies of the NASDAQ Biotechnology Index over a three-year performance period, subject to the NEO’s continued employment through the third anniversary of the grant date.
(3)The RSU awards to our NEOs were granted in February 2021 and vest one-fourth on each anniversary of the date of grant.
(4)The option awards to our NEOs were granted in February 2021 and vest one-fourth on the first anniversary of the date of grant and then 1/48 of the shares monthly over the three-year period thereafter.
(5)These amounts represent the grant date fair value of stock awards granted to our NEOs in fiscal year 2021 in accordance with the FASB ASC Topic 718. For information on the assumptions used in the accounting fair value computations, see footnotes (1) through (3) to the Summary Compensation Table above.

34
     Estimated Future Payouts Under
Non-Equity Incentive Plan Awards(1)
 Estimated Future Payouts Under
Equity Incentive Plan Awards
 All Other Stock Awards: Number of Shares or Units(#) All Other Option Awards: Number of Securities Underlying Options(#) Exercise or Base Price of Option Awards
($/Sh)
 Grant Date Fair Value of Stock and Option Awards($)
Name  Grant Date Thresh
-old
($)
 Target
($)
 Maximum
($)
 Thresh-
old
(#)
 Target
(#)
 Maximum
(#)
    
Helen I.
Torley
 n/a 
 570,750
 1,141,501
 
 
 
 

 

 

 

 2/12/2019 

 

 

 
 
 
 131,179
(2)




 2,184,130
   2/12/2019 

 

 

 
 
 
 


250,218
(3)16.65
 2,184,128
Laurie D. Stelzer n/a -
 222,750
 445,500
 
 
 
 

 

 

 

 2/12/2019 

 

 

 
 
 
 45,046
(2)




 750,016
   2/12/2019 

 

 

 
 
 
 


85,922
(3)16.65
 750,005
Harry J. Leonhardt n/a 
 208,800
 417,600
 
 
 
 

 




 

 2/12/2019 

 

 

 
 
 
 37,538
(2)




 625,008
  2/12/2019 

 

 

 
 
 
 

 71,602
(3)16.65
 625,007
Alison Armour n/a 
 95,979
 191,959
 
 
 
 

 




 

 6/3/2019 

 

 

 
 
 
 65,920
(4)




 1,000,006
   6/3/2019 
 
 
 
 
 
 

129,358
(5)15.17
 1,000,002
Benjamin J. Hickey n/a 
 217,350
 434,700
 
 
 
 

 




 

 2/12/2019 

 

 

 
 
 
 37,538
(2)




 625,008
   2/12/2019 

 

 

 
 
 
 

 71,602
(3)16.65
 625,007


________________
(1)For a description of the elements of the incentive plan applicable to our NEOs, refer to “Compensation Discussion and Analysis - Elements of Executive Compensation for 2019” in this proxy statement. The actual amount of cash paid to each NEO pursuant to the incentive plan established for 2019 is set forth in the Summary Compensation Table under the heading, “Non-Equity Incentive Plan Compensation.”
(2)These restricted stock unit awards were granted in February 2019 based on accomplishment of specified Company and individual performance criteria in fiscal 2018. These restricted stock unit awards have a grant date fair value of $16.65 per share and vest one-fourth on each anniversary of the date of grant.
(3)These option awards were granted in February 2019 based on accomplishment of specified Company and individual performance criteria in fiscal 2018. These option awards vest one-fourth on the first anniversary of the date of grant and then 1/48 of the shares monthly thereafter.
(4)This restricted stock unit award was granted in June 2019 as an inducement for Dr. Armour to join Halozyme. This restricted stock unit award has a grant date fair value of $15.17 per share and vests one-fourth on each anniversary of the date of grant.
(5)These option awards were granted in June 2019 as an inducement for Dr. Armour to join Halozyme. These option awards vest one-fourth on the first anniversary of the date of grant and then 1/48 of the shares monthly thereafter.


Outstanding Equity Awards at December 31, 20192021
The following table sets forth certain information with respect to the value of all unexercised options and unvested stock awards previously awarded to our NEOs as of December 31, 20192021:
OUTSTANDING EQUITY AWARDS AT DECEMBER 31, 2021
Option AwardsStock Awards
NameGrant DateNumber of Securities
Underlying Unexercised
Options (#) Exercisable
Number of Securities
Underlying Unexercised
Options (#) Unexercisable (1)
Option
Exercise
Price
($)
Option
Expiration
Date
Number of Shares
or Units of Stock
That Have Not Vested (#)(2)
Market Value
of Shares
or Units of Stock
That Have Not Vested
($)(3)
Equity Incentive Plan Awards:
Number of Unearned Shares,
Units or Other Rights
That Have Not Vested (#)(4)
Equity Incentive Plan Awards:
Market or Payout Value of
Unearned Shares, Units or
Other Rights That Have Not Vested
($) (3)
Helen I. Torley1/6/2014150,000 — 14.66 1/6/2024— — — — 
2/6/2015200,000 — 13.87 2/6/2025— — — 
2/3/2016376,569 — 8.11 2/3/2026— — — — 
2/22/2017251,923 — 12.07 2/22/2027— — — — 
2/14/2018193,154 8,398 18.41 2/14/202828,729 1,155,193 — — 
2/12/2019177,237 72,981 16.65 2/12/202965,589 2,637,334 — — 
2/10/2020121,939 144,112 19.98 2/10/203093,844 3,773,467 — — 
2/15/2021— 90,134 49.84 2/15/203152,368 2,015,717 22,868 919,522 
Elaine D. Sun3/2/202045,923 59,046 20.55 3/2/203036,496 1,467,504 — — 
4/1/2020— — — 4/1/2030— — 30,600 1,230,426 
2/15/2021— 25,642 49.84 2/15/203114,898 599,049 6,506 261,606 
Masaru Matsuda9/4/201882,708 — 18.16 9/4/2028— — — — 
2/12/201922,315 — 16.65 2/12/2029— — — — 
2/10/202024,387 — 19.98 2/10/2030— — — — 
2/15/2021— — 49.84 2/15/2031— — 3,494 140,494 
Michael J. LaBarre2/4/201534,000 — 13.81 2/4/2025— — — — 
2/3/201678,452 — 8.11 2/3/2026— — — — 
2/22/201756,352 — 12.07 2/22/2027— — — — 
2/14/201838,801 1,688 18.41 2/14/20285,771 232,052 — — 
7/2/20181,708 292 16.78 7/2/2028— — — — 
2/12/201942,602 17,544 16.65 2/12/202915,766 633,951 — — 
2/10/202031,703 37,471 19.98 2/10/203024,399 981,084 — — 
2/15/2021— 23,311 49.84 2/15/203113,544 544,604 5,914 237,802 
________________
(1):Each option vests at the rate of one-fourth of the underlying shares on the first anniversary of the date of grant and one-forty-eighth of the shares each month thereafter.
(2)Each RSU award vests one-fourth on each anniversary of the date of grant.
(3)These values are computed by multiplying the closing trading price of our common stock on NASDAQ on December 31, 2021, the last trading date in fiscal year 2021, of $40.21 by the number of shares or stock units, as applicable, set forth in this table.
(4)These PSU awards are eligible to be earned with respect to one-third of the target PSUs for one-, two- and three-year performance periods based on our relative TSR measured against the component companies of the NASDAQ Biotechnology Index. Earned shares vest 100% on the third anniversary of the grant date following certification of performance results and assuming continued employment through that date (subject to earlier vesting and payment on a pro-rated basis on certain terminations of employment as provided in the award agreement). The amounts reported in the table reflect the target number of PSUs that are eligible to vest based on performance during the 2021-2022 and 2021-2023 performance periods.

35
OUTSTANDING EQUITY AWARDS AT DECEMBER 31, 2019
     Option Awards Stock Awards
Name  Grant Date Number of Securities
Underlying Unexercised
Options (#) Exercisable
 Number of Securities
Underlying Unexercised
Options (#) Unexercisable(1)
 Option
Exercise
Price
($)
 Option
Expiration
Date
 Number of Shares
or Units of Stock
That Have Not Vested (#)(2)
 Market Value
of Shares
or Units of Stock
That Have Not Vested
($)(3)
Helen I. Torley 1/6/2014 700,000
 
 14.66
 1/6/2024 
 
  2/6/2015 200,000
 
 13.87
 2/6/2025 
 
  2/3/2016 360,878
 15,691
 8.11
 2/3/2026 55,487
 983,785
  2/22/2017 178,445
 73,478
 12.07
 2/22/2027 78,708
 1,395,493
  2/14/2018 92,378
 109,174
 18.41
 2/14/2028 86,188
 1,528,113
  2/12/2019 
 250,218
 16.65
 2/12/2029 131,179
 2,325,804
Laurie D. Stelzer 6/15/2015 225,000
 
 20.43
 6/15/2025 
 
  2/3/2016 100,244
 4,359
 8.11
 2/3/2026 23,119
 409,900
  2/22/2017 51,654
 21,271
 12.07
 2/22/2027 22,784
 403,960
  2/14/2018 25,107
 29,673
 18.41
 2/14/2028 23,425
 415,325
  2/12/2019 
 85,922
 16.65
 2/12/2029 45,046
 798,666
Harry J. Leonhardt 4/13/2015 225,000
 
 15.63
 4/13/2025 
 
  2/3/2016 100,244
 4,359
 8.11
 2/3/2026 15,413
 273,272
  2/22/2017 51,654
 21,271
 12.07
 2/22/2027 22,784
 403,960
  2/14/2018 25,107
 29,673
 18.41
 2/14/2028 23,425
 415,325
  2/12/2019 
 71,602
 16.65
 2/12/2029    
Alison Armour 6/3/2019 
 129,358
 15.17
 6/3/2029 65,920
 1,168,792
Benjamin J. Hickey 10/1/2018 43,608
 105,908
 18.55
 10/1/2028 60,647
 1,075,271
   2/12/2019 
 71,602
 16.65
 2/12/2029 37,538
 665,549

________________

(1)Each option vests at the rate of 1/4 of the underlying shares on the first anniversary of the date of grant and 1/48 of the shares each month thereafter.
(2)Each restricted stock unit award vests one-fourth on each anniversary of the date of grant.
(3)Computed by multiplying the closing market price of our common stock on December 31, 2019, the last trading date in fiscal year 2019, of $17.73 by the number of shares or stock units, as appropriate, set forth in this table.




Option Exercises and Stock Awards Vested
The following table sets forth certain information with respect to the exercise of stock options and vesting of stock awards by our NEOs during the fiscal year ended December 31, 20192021:
OPTION EXERCISES AND STOCK AWARDS VESTED DURING FISCAL YEAR 2021
Option AwardsStock Awards
NameNumber of
Shares Acquired
on Exercise
(#)
Value Realized
on Exercise
($)(1)
Number of
Shares Acquired
on Vesting
(#)(2)
Value Realized
on Vesting
($)(3)
Helen I. Torley500,000 14,100,933 132,160 6,565,372 
Elaine D. Sun— — 22,362 980,208 
Masaru Matsuda— — 17,269 812,994 
Michael J. LaBarre132,500 4,418,020 30,591 1,520,714 
________________
(1):The value realized on exercise is based on the difference between the closing trading price of Halozyme common stock on the date of exercise and the exercise price of each option.
(2)The amounts in this column represent the number of RSU or PSU shares that vested. The actual number of shares issued was the number of shares vested reduced by the number of shares withheld to satisfy applicable tax withholding obligations.
(3)The value realized on vesting is based on the closing trading price of Halozyme common stock NASDAQ on the vest date.
36
OPTION EXERCISES AND STOCK AWARDS VESTED DURING FISCAL YEAR 2019
   Option Awards Stock Awards
Name  Number of
Shares Acquired
on Exercise
(#)
 Value Realized
on Exercise
($)(1)
 Number of
Shares Acquired
on Vesting
(#)(2)
 Value Realized
on Vesting
($)(3)
Helen I. Torley 
 
 154,821
 2,553,998
Laurie D. Stelzer 
 
 49,195
 801,482
Harry J. Leonhardt 
 
 41,489
 682,830
Alison Armour 
 
 
 
Benjamin J. Hickey 
 
 20,216
 312,539

________________

(1)The value realized on exercise is based on the difference between the closing sale price of Halozyme common stock on the date of exercise and the exercise price of each option.
(2)The amounts in this column represent the number of stock award shares vested. The actual number of shares issued was the number of shares vested reduced by the number of shares surrendered as payment for withholding taxes.
(3)The value realized on vesting is based on the closing sale price of Halozyme common stock on the vest date.
Potential Payments Upon Termination or Change in Control
Severance PolicyThis section describes the benefits that may be provided to our NEOs (other than Mr. Matsuda) upon certain terminations of their employment with the Company. The terms of Mr. Matsuda’s separation agreement with the Company are described below.
The Compensation Committee has approved a company-wideTermination Prior to Change in Control
Under our severance policy, thatif an executive officer’s employment is also applicable to executive officers interminated by the following respect: the cash severance forCompany without cause, the executive officer will beis entitled to receive cash severance equal to (i)one times (in the case of the CEO, one and one-half times) the executive officer’s then-current annual base salary, (1.5X forplus a pro-rated portion of the CEO), plus (ii) a pro-rata amount equal to the executive officer’sexecutive’s target annual bonus opportunity for the year during which the separation of employment occurs based on the number of days employed during the year.termination. Cash payments under the severance policy will normally be made in a lump sum payment, subject to standard taxes and withholdings, and will be conditioned upon the receipt of a release of claims from the executive officer. In addition to cash severance payments, the Company will also allowpay certain costs for the executive to continue healthcare coverage over the applicable severance period, and the executive’s vested stock options (at the time of separation) to bewill remain exercisable for one year fromfollowing the termination date (or, if earlier, until the expiration date of separation (or when the option expires,option).
The PSU awards granted to our NEOs in 2021 provide that if earlier)the executive’s employment is terminated by the Company without cause or by the executive for good reason and pay certain health coverage coststhe executive provides a release of claims, any PSUs credited based on performance during a performance period that has already been completed will fully vest on the executive’s termination, and PSUs subject to a performance period that has not yet been completed will remain outstanding and eligible to vest based on performance during that period, subject to pro-ration to reflect the executive’s employment during the termperformance period. If the executive’s employment terminates due to the executive’s death or disability, any PSUs credited based on performance during a performance period that has already been completed will fully vest on the executive’s termination, and the target number of PSUs for the applicable severancenext performance period scheduled to be completed after the termination date will vest pro-rata based on the executive’s employment during that performance period. DespiteThe table below presents the establishment of the severance policy, however, the Board of Directors or Compensation Committee retains the rightbenefits that would be provided to amend, alter or terminate the severance policy at any time.



Under the policy (or special severance agreement, as applicable), assuming: (i) each of the NEOs (other than Mr. Matsuda, whose separation agreement is described below) assuming the NEO was terminated by us without cause or terminates for good reason (as such terms are defined(prior to a change in control of the Severance Policy or special severance agreement)Company) on December 31, 2019;2021 and (ii) each NEO executed a release of claims in a form satisfactory to the Company,Company:
NameLump Sum
Severance
Payment
Post-
Termination
Healthcare
Equity Awards (1)Total
Helen I. Torley$1,909,509 $39,920 $635,238 $2,584,667 
Elaine D. Sun716,300 37,920 180,785 935,005 
Michael J. LaBarre716,300 2,536 206,559 925,395 

________________
(1)Amounts shown in this column reflect the spread value of unvested options (i.e. the amount by which the market value of the shares subject to the unvested options exceeded the exercise price of the unvested options) and market value of unvested RSUs or PSUs, in each case that would have accelerated if the NEO was terminated without cause (or resigned for good reason) as described above on December 31, 2021. Values were derived using the closing trading price of our common stock on NASDAQ on December 31, 2021, the last trading date in fiscal year 2021, of $40.21. The number of accelerated PSUs for the 2021 performance period was determined based on our relative TSR through December 31, 2021. We did not include any amount for the PSUs allocated to the 2021-2022 and 2021-2023 performance periods because the number of PSUs that will vest with respect to those periods is not known as it will depend on our future performance. These amounts were calculated solely for purposes of this disclosure, and there can be no assurance that the value actually be realized by the executive for these awards (if any) will be equal to the value shown in this column.

The table below presents the benefits that would be provided to each of the NEOs (other than Mr. Matsuda, whose separation agreement is described below) assuming the NEO’s employment terminated due to death or disability (prior to a change in control of the Company) on December 31, 2021:

2021 Potential Payments Upon Termination Due to Death/Disability Prior to Change in Control
NameEquity Awards (1)
Helen I. Torley$541,830 
Elaine D. Sun154,206 
Michael J. LaBarre182,393 
37


________________
(1)Amounts shown in this column reflect the spread value of unvested equity awards that would have receivedaccelerated if the following amounts pursuantNEO’s employment terminated due to death or disability on December 31, 2021. Please see the note to the severance policy:2021 Potential Payments Upon Termination Without Cause Prior to Change in Control table above for the calculation of these amounts. The number of accelerated PSUs for the 2021 performance period was determined based on our relative TSR through December 31, 2021, and the number of accelerated PSUs for the 2021-2022 performance period represents the target number of PSUs allocated to that period (pro-rated for the executive’s period of employment). These amounts were calculated solely for purposes of this disclosure, and there can be no assurance that the value actually be realized by the executive for these awards (if any) will be equal to the value shown in this column.
Name  Lump Sum
Severance
Payment
 Post-
Termination
Healthcare
Helen I. Torley 
$1,712,251
 $36,787
Laurie D. Stelzer 
$717,750
 $24,525
Harry J. Leonhardt 
$672,800
 $11,242
Alison Armour 
$641,466
 $24,525
Benjamin J. Hickey 
$941,850
 $52,504
Change in Control
We have entered into Change in Control Agreements with each of our executive officers. The Change in Control Agreements provide for cash payments,severance, continued healthcare coverage and accelerated vesting of equity awards for any suchif the executive officer who is terminated without cause, resigns for agood reason, other than causeor is terminated due to death or disability (as such terms are defined in the Change in Control Agreements), in each case on or within 12 months following a change in control transaction. The cash payments,severance, to be made in a lump sum payment, will equal: a multiple (two times for the Company's CEO and one-and-a-halfone-and-one-half times for the other executive officers) of the sum of (i) the executive’s then-current annual base salary; and (ii) the amount of the executive’s target annual bonus opportunity (based on the target percentage of annual base salary) in respect of the year the termination of employment occurs. The Company will also make a cash lump sum payment intended to provide the executive officer sufficient amounts to pay expected heath care premiums under the Company’s group health plans for 18 months postafter termination of employment (24 months in the case of the CEO). In addition, the Change in Control Agreement provides that the executive’s outstanding and unvested equity awards granted by the Company will be fully vested upon the executive’s termination (with equity awards that are subject to performance-based vesting to accelerate based on the greater of (x) the target performance level for the applicable portion of the award and (y) the actual performance level achieved for the applicable portion of the award through the executive’s termination date). However, the PSU awards granted to the NEOs in 2021 and 2022 provide that if a change in control occurs any performance period then in progress will terminate and the number of PSUs to be credited under the award will be determined based on performance through the change in control. Such credited PSUs will remain subject to time-based vesting through the third anniversary of the grant date, subject to accelerated vesting if the credited PSUs are not assumed by the acquiring company or if within two years after the change in control the executive’s employment is terminated by the Company without cause, by the executive for good reason, or due to the executive’s death or disability. An executive officer will not be entitled to severance benefits under our severance policy described above if the executive is entitled to severance benefits under their Change in Control Agreement. The Change in Control Agreements also provide that the amount ofif an executive officer’s severance benefits could potentiallywould be subject to reduction to the extent that the total payments (as defined in the Change in Control Agreements) constitute an “excess parachute payment” under Sectionpayment taxes of Sections 280G and 4999 of the Internal Revenue Code of 1986, as amended, orand a reduction in benefits to avoid such taxes would put the Code or become subjectexecutive in a better after-tax position, then the executive’s benefits will be reduced to the excise tax imposed under Section 4999 of the Code.extent necessary to avoid such taxes.
Assuming a change in control took place on December 31, 20192021 and each of the NEOs was terminated without cause, resignsresigned for good reason or iswas terminated due to death or disability (as such terms are defined in each case on December 31, 2021, the Change in Control Agreements) on or within 12 months following the change in control, the foregoing individualsNEOs (other than Mr. Matsuda, whose separation agreement is described below) would have received the following amountsbenefits as a result of such terminations:
20202021 Potential Payments Upon Change in Control Termination
Name  Equity
Awards(1)
 Lump Sum
Cash Severance
 Post-
Termination
Healthcare
 Total
Helen I. Torley 
$7,070,263
 
$2,663,502
 
$72,132
 
$9,805,897
Laurie D. Stelzer 
$2,282,974
 
$1,076,626
 
$54,099
 
$3,413,699
Harry J. Leonhardt 
$1,997,764
 
$1,009,200
 
$24,799
 
$3,031,763
Alison Armour 
$1,499,918
 
$1,076,625
 
$54,099
 
$2,630,642
Benjamin J. Hickey 
$1,818,150
 
$1,050,526
 
$77,212
 
$2,945,888
NameEquity
Awards (1)
Lump Sum
Cash Severance
Post-
Termination
Healthcare
Total
Helen I. Torley$15,409,128 $2,988,797 $78,274 $18,476,199 
Elaine D. Sun$4,719,429 $1,074,450 $83,647 $5,877,526 
Michael J. LaBarre$3,844,508 $1,074,450 $5,595 $4,924,553 
________________
(1)Amounts shown in this column reflect the value of unvested options and market value of unvested restricted stock units that would have accelerated if the NEO was terminated on December 31, 2019 in connection with a change in control. Values were derived using the closing market price of our common stock on December 31, 2019, the last trading date in fiscal year 2019, of $17.73. There can be no assurance that the options will ever be exercised (in which case no value will actually be realized by the executive) or that the value on exercise will be equal to the value shown in this column.

(1)Amounts shown in this column reflect the value of the unvested equity awards that would have accelerated if the NEO’s employment terminated in the circumstances described above on December 31, 2021 in connection with a change in control. Please see the note to the 2021 Potential Payments Upon Termination Without Cause Prior to Change in Control table above for the calculation of these amounts. The number of accelerated PSUs was determined based on our relative TSR through December 31, 2021. These amounts were calculated solely for purposes of this disclosure and there can be no assurance that the value actually realized by the executive for these awards (if any) will be equal to the value shown in this column.


38


Masaru Matsuda’s Separation Agreement

Mr. Matsuda separated employment from the Company, effective December 31, 2021. The Company and Mr. Matsuda entered into a separation agreement that provides for Mr. Matsuda to receive the benefits provided under our severance policy described above: cash severance of 12 months of his base salary, his annual bonus for 2021 (with no pro-ration as he was employed with the Company for the entire year), payment for continued health coverage for him and his eligible dependents, and an extension of the period to exercise his vested options for up to 12 months following his termination. Mr. Matsuda is also eligible for pro-rata vesting of his PSU award granted in 2021, with the award to remain outstanding and eligible to vest based on performance for each applicable performance period and with vesting for each performance period pro-rated to reflect the portion of the performance period that Mr. Matsuda was employed with the Company. The separation agreement includes a general release of claims by Mr. Matsuda.

39


Compensation of Directors
The following table sets forth information concerning the compensation earned during the fiscal year ended December 31, 20192021 by each individual who served as a non-employee director at any time during the fiscal year:
2019 DIRECTOR COMPENSATION
2021 DIRECTOR COMPENSATION2021 DIRECTOR COMPENSATION
Name Fees Earned
or Paid in Cash
($)
 Stock Awards
($)(1)(2)
 Total
($)
NameFees Earned
or Paid in Cash
($)
Stock Awards
($)(1)(2)
Total
($)
Jean-Pierre BizzariJean-Pierre Bizzari 60,000 200,002 260,002Jean-Pierre Bizzari61,676250,046311,722
Bernadette ConnaughtonBernadette Connaughton 66,621 200,002 266,623Bernadette Connaughton70,000250,046320,046
James M. DalyJames M. Daly 55,000 200,002 255,002James M. Daly70,000250,046320,046
Jeffrey W. HendersonJeffrey W. Henderson 90,000 200,002 290,002Jeffrey W. Henderson90,000250,046340,046
Kenneth J. Kelley 75,000 200,002 275,002
Kenneth J. Kelley(3)Kenneth J. Kelley(3)25,13725,137
Connie L. MatsuiConnie L. Matsui 105,000 200,002 305,002Connie L. Matsui115,000250,046365,046
Matthew L. PosardMatthew L. Posard 70,000 200,002 270,002Matthew L. Posard75,000250,046325,046
________________
(1)Represents the grant date fair value of restricted stock unit awards granted in fiscal year 2021 in accordance with FASB ASC Topic 718.
(2)The aggregate numbers of shares subject to restricted stock unit awards held by the non-employee directors as of December 31, 2021 are described below:
(1)Represents the grant date fair value of restricted stock awards granted in fiscal year 2019 in accordance with FASB ASC Topic 718.
(2)The aggregate numbers of shares subject to restricted stock awards held by the non-employee directors as of December 31, 2019 are described below:
NameAggregate Number 
of Stock Awards
Outstanding
(#)
Jean-Pierre Bizzari12,1735,230
Bernadette Connaughton12,1735,230
James M. Daly12,1735,230
Jeffrey W. Henderson12,1735,230
Kenneth J. Kelley(3)
12,173
Connie L. Matsui12,1735,230
Matthew L. Posard12,1735,230


(3) Mr. Kelley resigned as a director effective May 1, 2021.
40





Directors’ Compensation
Effective December 2015, the equityThe compensation program for our non-employee directors is as follows:
(1) Initial award - each non-employee director receives an initial restricted stock unit grant of common stock having a grant date value of $200,000$250,000 (with the number of shares of Company common stock subject to the award equal to $200,000$250,000 divided by the closing trading price of the Company’s common stock on NASDAQ on the date of grant, with any fraction rounded up to the nearest whole share) upon joining the Board; provided that, the numbersgrant date value of shares grantedthe award for directorsa director first elected or appointed between Annual Meetings shall be prorated based on the number of full quarters the individual is scheduled to serve as a non-employee director from the date of election or appointment until the next Annual Meeting of the stockholdersStockholders such that the recipient will receive a grant of restricted stock units valued at $150,000$187,500 for a period of service exceeding 270 days,three quarters, a grant of restricted stock units valued at $100,000$125,000 for a period of service exceeding 180 daystwo-quarters (but no more than 270 days)three quarters), a grant of restricted stock units valued at $50,000$62,500 for a period of service exceeding 90 daysone quarter (but no more than 180 days)two quarters), and no sharesaward for a period of service of 90 daysone quarter or less. Subject to acceleration in the event of a change of control of the Company, this initial restricted stock unit grant will vest upon the date of the next Annual Meeting following the date of the initial restricted stock unit grant.
(2) Annual award - Non-employee directors alsoImmediately following each Annual Meeting, each non-employee director then in office automatically receivereceives an annual restricted stock grants of common stockunit grant having a value of $200,000$250,000 (with the number of shares of Company common stock subject to the award equal to $200,000$250,000 divided by the closing trading price of the Company’s common stock on NASDAQ on the date of grant, with any fraction rounded up to the nearest whole share) immediately following future Annual Meetings.. Subject to acceleration in the event of a change of control of us,the Company, this annual restricted stock unit grant will vest in full on the earlier of (i) the first anniversary of the date of grant or (ii) the date of the next Annual Meeting following the date of the annual restricted stock unit grant. All restricted stock unit awards will beafter our 2021 annual meeting are granted under our Amended and Restated 20112021 Stock Plan.
Our non-employee directors also receive an annual retainer of $50,000 for service on the Board, provided that our Chair of the Board of Directors receives an annual retainer of $85,000,$125,000, as well as an additional annual retainer for service on any committee of the Board. Non-employee directors who serve on the Audit Committee receive an annual retainer of $15,000, provided that the Chair of that committee receives an annual retainer of $30,000. Non-employee directors who serve on the Compensation Committee receive an annual retainer of $10,000, provided that the Chair of that committee receives an annual retainer of $20,000. Non-employee directors who serve on the Nominating and Corporate Governance Committee receive an annual retainer of $5,000, provided that the Chair of that committee receives an annual retainer of $10,000. Employee directors (including our CEO) do not receive any compensation for service on the Board of Directors.
We also maintain stock ownership guidelines for our non-employee directors which stipulate that each non-employee director is expected to own shares of Halozyme common stock with value equal to no less than five times the non-employee director’s base annual retainer for service on the Board of Directors. Each non-employee director is expected to comply with the guidelines within five years of election or appointment to the Board of Directors. Share ownership that counts for purposes of satisfying the applicable guideline level of ownership is the same as under our executive stock ownership guidelines, as described in the CD&A above. The same retention requirements apply to a non-employee director whose level of stock ownership does not satisfy the applicable guideline level of ownership as under our executive stock ownership guidelines, as described in the CD&A above.
In 2021, the Company adopted the Halozyme Nonqualified Deferred Compensation Plan (the “Cash Deferral Plan”) and the Halozyme Therapeutics, Inc. Directors Deferred Equity Compensation Plan (the “Equity Deferral Plan”), each to take effect in 2022. Under the Cash Deferral Plan, a non-employee director may elect to defer payment of all or a portion of the director’s annual cash compensation, deferrals are credited with earnings or losses based on investment fund elections made by the director, and the deferred amounts (as adjusted for such earnings or losses) will be paid to the director (in a lump sum or annual installments over up to five years, as elected by the director) when the director no longer serves on the Board of Directors or an earlier distribution date elected by the director in accordance with the plan. Under the Equity Deferral Plan, a non-employee director may elect (1) to convert all or a portion of the director’s annual cash compensation into Company restricted stock units awarded under our 2021 Stock Plan and/or (2) to defer the payment of the director’s annual restricted stock unit award from the Company. If a non-employee director elects to convert all or a portion of the director’s cash retainers into restricted stock units, the director will be credited with additional restricted stock units on the date the retainers would have otherwise been paid to the
41


director equal to (1) the amount being deferred to the Equity Deferral Plan that would have otherwise been paid to the director on that date, divided by (2) the average closing price for a share of Company common stock over the period of ten consecutive trading days ending with the last trading day prior to the crediting date. Deferred restricted stock units will be credited with dividend equivalents to preserve the value of the awards if/when the Company were to ever pay a dividend. A non-employee director’s deferred restricted stock units will be paid in Company common stock (in a lump sum or annual installments over up to five years as elected by the director) when the director no longer serves on the Board of Directors or, if earlier, upon a change in control of the Company.

CEO Pay Ratio

For 2019,2021, Dr. Torley’s total compensation was $5,857,126.25,$7,453,294, as shown in the Summary Compensation Table.Table above. The total compensation for theour median employee (excluding the CEO) in 20192021 was $238,096.$291,734. Therefore, Dr. Torley’s total compensation for 20192021 was 2526 times that of the median employee’s total compensation in 2019.2021. The Company believes the pay ratio reported above is a reasonable estimate calculated in a manner consistent with SEC rules based on our payroll and employment records, as well as the methodology described below.
The compensation elements that were considered in the identification of the median employee were annualized base pay, target cash bonus opportunity and target long-term incentive award grant date fair value for 20172020 for all employees, excluding the CEO, and non-USas of December 31, 2020. The total number of our employees as of December 31, 2017. The total number of employees as of December 31, 20172020 (excluding the CEO) was 255 of which 251 were included in the131. We used this population used to determine the median employee. For 2019, a substitute median employee was selected with compensation comparable to the original median employee, because the original median employee was terminated. Once identified, theThe total compensation for the median employee was calculated according to the requirements of the Summary Compensation Table.
CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS
Pursuant to our Code of Conduct and Ethics, our executive officers, directors, and principal stockholders, including their immediate family members and affiliates, are prohibited from entering into transactions which create, or would appear to create, a conflict of interest with us. Our Audit Committee is responsible for reviewing and approving related party transactions. Our Audit Committee shall approve only those agreements that, in light of known circumstances, are in, or are not inconsistent with, our best interests, as our Audit Committee determines in the good faith exercise of its discretion.

42


SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND RELATED STOCKHOLDER MATTERS
The following table sets forth, as of March 2, 2020,7, 2022, certain information with respect to the beneficial ownership of our common stock by (i) each stockholder known by Halozyme to be the beneficial owner of more than 5% of our common stock, (ii) each director and director-nominee of Halozyme, (iii) each executive officer named in the Summary Compensation Table above, and (iv) all directors and current executive officers of Halozyme as a group:
Beneficial Owner(1)Number of Shares
Beneficially
Owned(2)
Percent(3)
BlackRock, Inc19,439,863 (4)13.9%
55 East 52nd Street, New York, NY 10055
Vanguard Group Inc.13,495,913 (5)9.7%
100 Vanguard Blvd., Malvern, PA 19355
Artisan Partners Limited Partnership9,505,768 (6)6.8%
875 East Wisconsin Avenue, Suite 800, Milwaukee, WI 53202
Helen I. Torley2,135,707 (7)1.5%
Elaine D. Sun64,315 (8)*
Michael J. LaBarre476,227 (9)*
Masaru Matsuda150,753 (10)*
Jean-Pierre Bizzari52,544 *
Bernadette Connaughton32,013 *
James M. Daly26,232 *
Jeffrey W. Henderson52,839 *
Connie L. Matsui181,983 *
Matthew L. Posard128,983 *
Moni Miyashita— *
Directors and current executive officers as a group (11 persons)3,176,296 2.3%
________________
*    Less than 1%.
(1)Except as otherwise indicated, the persons named in this table have sole voting and investment power with respect to all shares of common stock shown as beneficially owned by them, subject to community property laws where applicable and to the information contained in the footnotes to this table. Unless otherwise noted, the address for each beneficial owner is: c/o Halozyme Therapeutics, Inc., 11388 Sorrento Valley Road, San Diego, CA 92121.
(2)Under the rules of the Securities and Exchange Commission, a person is deemed to be the beneficial owner of shares that can be acquired by such person within 60 days upon the exercise of options or warrants and vesting of stock awards.
(3)Calculated on the basis of 137,772,750 shares of common stock outstanding as of March 7, 2022, provided that any additional shares of common stock that a stockholder has the right to acquire within 60 days after March 7, 2022 are deemed to be outstanding for the purpose of calculating that stockholder’s percentage beneficial ownership.
(4)Based on Schedule 13G/A filed by BlackRock, Inc. with the SEC on January 28, 2022. BlackRock, Inc. beneficially owned 19,439,863 shares, with sole voting power over 19,026,859 shares and sole dispositive power over
43


Beneficial Owner(1)  
Number of Shares
Beneficially
Owned(2)
 Percent(3)
Vanguard Group Inc. 14,023,459
(4)10.2%
100 Vanguard Blvd., Malvern, PA 19355    
BlackRock, Inc. 12,096,797
(5)8.8%
55 East 52nd Street, New York, NY 10055    
BB Biotech AG 7,963,056
(6)5.8%
Schwertstrasse 6, CH-8200 Schaffhausen, Switzerland    
Helen I. Torley 2,148,682
(7)1.6%
Laurie D. Stelzer 568,233
(8)*
Harry J. Leonhardt 453,536
(9)*
Alison Armour 

0
Benjamin J. Hickey 
 
Jean-Pierre Bizzari 73,485

*
Bernadette Connaughton 17,954

*
James M. Daly 56,873

*
Jeffrey W. Henderson 63,278

*
Kenneth J. Kelley 224,924

*
Connie L. Matsui 239,924

*
Matthew L. Posard 114,924

*
Directors and current executive officers as a group (11 persons) 3,542,562

2.6%
19,439,863 shares and shared voting and dispositive power over 0 shares, which shares are reported by BlackRock, Inc. as a parent holding company of its subsidiaries.
________________
*Less than 1%.
(1)Except as otherwise indicated, the persons named in this table have sole voting and investment power with respect to all shares of common stock shown as beneficially owned by them, subject to community property laws where applicable and to the information contained in the footnotes to this table. Unless otherwise noted, the address for each beneficial owner is: c/o Halozyme Therapeutics, Inc., 11388 Sorrento Valley Road, San Diego, CA 92121.
(2)Under the rules of the Securities and Exchange Commission, a person is deemed to be the beneficial owner of shares that can be acquired by such person within 60 days upon the exercise of options or warrants and vesting of stock awards.
(3)Calculated on the basis of 138,069,410 shares of common stock outstanding as of March 2, 2020, provided that any additional shares of common stock that a stockholder has the right to acquire within 60 days after March 2, 2020 are deemed to be outstanding for the purpose of calculating that stockholder’s percentage beneficial ownership.
(4)Based on Schedule 13G/A filed by The Vanguard Group with the SEC on February 10, 2020. The Vanguard Group beneficially owned 14,023,459 shares, with sole voting power over 296,478 shares, shared voting power over 16,566


(5)Based on Schedule 13G/A filed by The Vanguard Group with the SEC on February 10, 2022. The Vanguard Group beneficially owned 13,495,913 shares, with sole voting power over 0 shares, shared voting power over 262,161 shares, sole dispositive power over 13,727,87913,105,630 shares and shared dispositive power over 295,580390,283 shares, which shares are reported by The Vanguard Group as in its own capacity and on behalf of its subsidiaries.
(5)Based on Schedule 13G/A filed by BlackRock, Inc. with the SEC on February 10, 2020. BlackRock, Inc. beneficially owned 12,096,797 shares, with sole voting power over 11,850,406 shares and sole dispositive power over 12,096,797 shares, which shares are reported by BlackRock, Inc. as a parent holding company of its subsidiaries.
(6)Based on Schedule 13G/A filed by BB Biotech AG and Biotech Target N.V. with the SEC on February 14, 2020. BB Biotech AG and its wholly owned subsidiary, Biotech Target N.V., held shared voting and dispositive power over 7,963,056 shares.
(7)Includes 1,658,160 shares subject to options that may be exercised within 60 days after March 2, 2020.
(8)Includes 442,066 shares subject to options that may be exercised within 60 days after March 2, 2020.
(9)Includes 429,586 shares subject to options that may be exercised within 60 days after March 2, 2020.


(6)Based on Schedule 13G/A filed by Artisan Partners Limited Partnership (and affiliated companies pursuant to a joint filing agreement) with the SEC on February 4, 2022. Artisan beneficially owned 9,505,768 shares, with shared voting power over 7,886,482 shares and shared dispositive power over 9,505,768 shares and sole voting and dispositive power over 0 shares.
(7)Includes 1,548,530 shares subject to options that may be exercised within 60 days after March 7, 2022.
(8)Includes 50,297 shares subject to options that may be exercised within 60 days after March 7, 2022.
(9)Includes 303,090 shares subject to options that may be exercised within 60 days after March 7, 2022.
(10)Includes 129,410 shares subject to options that may be exercised within 60 days after March 7, 2022.

44


STOCKHOLDER PROPOSALS TO BE PRESENTED AT NEXT ANNUAL MEETING
Stockholder proposals may be included in our proxy materials for an Annual Meeting so long as they are provided to us on a timely basis and satisfy the other conditions set forth in applicable SEC rules. For a stockholder proposal to be included in our proxy materials for the 20212023 Annual Meeting, the proposal must be received at our principal executive offices, addressed to the Secretary, not later than November 20, 2020.25, 2022.
Stockholder business that is not intended for inclusion in our proxy materials may be brought before the 20212023 Annual Meeting so long as we receive notice of the proposal as specified by our Bylaws, addressed to the Secretary at our principal executive offices, not later than November 20, 2020,25, 2022, in accordance with the specific procedural requirements in our Bylaws. Failure to comply with our Bylaw procedures and deadlines may preclude presentation of the proposal at our 20212023 Annual Meeting.
TRANSACTION OF OTHER BUSINESS
At the date of this Proxy Statement, the Board of Directors knows of no other business that will be conducted at the 20202022 Annual Meeting other than as described in this Proxy Statement. If any other matter or matters are properly brought before the meeting, or any adjournment or postponement of the meeting, it is the intention of the persons named in the accompanying form of proxy to vote the proxy on such matters in accordance with their best judgment.

45


DELIVERY OF PROXY MATERIALS AND ANNUAL REPORTS
We may satisfy SEC’s rules regarding delivery of proxy statements and annual reports by delivering a single proxy statement and annual report to an address shared by two or more stockholders. This process is known as “householding.” This delivery method can result in meaningful cost savings for us. In order to take advantage of this opportunity, we have delivered only one proxy statement and annual report to multiple stockholders who share an address, unless contrary instructions were received prior to the mailing date. Accordingly, for many stockholders who hold their shares through a bank, brokerage firm or other holder of record (i.e., in “street name”) and share a single address, only one annual report and proxy statement is being delivered to that address unless contrary instructions from any stockholder at that address were received.
We undertake to deliver promptly upon written or oral request a separate copy of the proxy statement and/or annual report, as requested, to a stockholder at a shared address to which a single copy of these documents was delivered. If you hold stock as a record stockholder and prefer to receive separate copies of a proxy statement or annual report either now or in the future, please contact our Secretary at 11388 Sorrento Valley Road, San Diego, California 92121, or by telephone at (858) 794-8889. If your stock is held by a brokerage firm or bank and you prefer to receive separate copies of a proxy statement or annual report either now or in the future, please contact your brokerage or bank. The voting instruction sent to a street-name stockholder should provide information on how to request (1) householding of future company materials or (2) separate materials if only one set of documents is being sent to a household. If it does not, a stockholder who would like to make one of these requests should contact us as indicated above.
By order of the Board of Directors,
svpsignaturea02.jpgmarkssignaturea.jpg
Masaru Matsuda, ESQ.Mark Snyder
Senior Vice President, General Counsel,
and Corporate Secretary
March 20, 202025, 2022
46

































Important Notice Regarding the Availability of Proxy Materials for the Annual Meeting: The Annual Report, and Notice & Proxy Statement is/are available at www.proxyvote.com
PROXY
HALOZYME THERAPEUTICS, INC.
PROXY SOLICITED BY THE BOARD OF DIRECTORS
FOR THE ANNUAL MEETING OF STOCKHOLDERS
TO BE HELD ON APRIL 30, 2020MAY 5, 2022

www.virtualshareholdermeeting.com/HALO2022
The undersigned hereby appoints Helen I. Torley and Masaru Matsuda,Mark Snyder, and each of them, as attorneys and proxies of the undersigned, with full power of substitution, to vote all of the shares of stock of Halozyme Therapeutics, Inc. (the “Company”) which the undersigned may be entitled to vote at the Annual Meeting of Stockholders of the Company to be held at the main office of Halozyme Therapeutics, Inc., 11388 Sorrento Valley Road, San Diego, California 92121,online on Thursday, April 30, 2020,May 5, 2022, at 8:00 a.m. local timePacific Time and at any and all adjournments or postponements thereof, with all powers that the undersigned would possess if personally present, upon and in respect of the following matters and in accordance with the following instructions, with discretionary authority as to any and all other matters that may properly come before the meeting.
The shares represented by this proxy card will be voted as directed or, if this card contains no specific voting instructions, these shares will be voted in accordance with the recommendations of the Board of Directors.
YOUR VOTE IS IMPORTANT. You are urged to complete, sign, date and promptly return the accompanying proxy in the enclosed envelope, which is postage prepaid if mailed in the United States.



(Continued and to be signed on reverse side.)




scantoa.jpg
HALOZYME THERAPEUTICS, INC.
11388 SORRENTO VALLEY ROAD
SAN DIEGO, CA 92121
VOTE BY INTERNET - www.proxyvote.com
Use the Internet to transmit your voting instructions and for electronic delivery of information up until 11:59 P.M. Eastern Time the day before the cut-off date or meeting date. Have your proxy card in hand when you access the web site and follow the instructions to obtain your records and to create an electronic voting instruction form.
HALOZYME THERAPEUTICS, INC.
11388 SORRENTO VALLEY ROAD
SAN DIEGO, CA 92121
ELECTRONIC DELIVERY OF FUTURE PROXY MATERIALS
If you would like to reduce the costs incurred by our company in mailing proxy materials, you can consent to receiving all future proxy statements, proxy cards and annual reports electronically via e-mail or the Internet. To sign up for electronic delivery, please follow the instructions above to vote using the Internet and, when prompted, indicate that you agree to receive or access proxy materials electronically in future years.
VOTE BY PHONE - 1-800-690-6903
Use any touch-tone telephone to transmit your voting instructions up until 11:59 P.M. Eastern Time the day before the cut-off date or meeting date. Have your proxy card in hand when you call and then follow the instructions.
VOTE BY MAIL
Mark, sign and date your proxy card and return it in the postage-paid envelope we have provided or return it to Vote Processing, c/o Broadridge, 51 Mercedes Way, Edgewood, NY 11717.









TO VOTE, MARK BLOCKS BELOW IN BLUE OR BLACK INK AS FOLLOWS:x
KEEP THIS PORTION FOR YOUR RECORDS
DETACH AND RETURN THIS PORTION ONLY
THIS PROXY CARD IS VAIDVALID ONLY WHEN SIGNED AND DATED.



For
All
Withhold
All
For All ExceptTo withhold authority to vote for any individual nominee (s), mark “For All Except” and write the number of the nominee(s) on the line below.
The Board of Directors recommends you vote FOR the following:
ooo
1Election of Class IIII Directors
NomineesForAgainstAbstain
01 Bernadette Connaughton1A Jeffrey W. Henderson02 Kenneth J. Kelley03 Matthew L. Posardooo
1B Connie L. Matsuiooo
1C Helen I. Torleyooo
The Board of Directors recommends you vote FOR proposals 2 and 3.ForAgainstAbstain
2To approve, by a non-binding advisory vote, the compensation of the Company's named executive officers.ooo
3To ratify the selection of Ernst & Young LLP as the Company’s independent registered public accounting firm for the fiscal year ending December 31, 2020.2022.ooo
NOTE: Such other business as may properly come before the meeting or any adjournment thereof.
Please sign exactly as your name(s) appear(s) hereon. When signing as attorney, executor, administrator, or other fiduciary, please give full title as such. Joint owners should each sign personally. All holders must sign. If a corporation or partnership, please sign in full corporate or partnership name by authorized officer.
Signature [PLEASE SIGN WITHIN BOX]DateSignature (Joint Owners)Date